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• W189616045 endingPage "255" @default.
• W189616045 startingPage "195" @default.
• W189616045 abstract "Polycyclic aromatic hydrocarbons (PAHs) are derived from both natural and anthropogenic sources and are released from a wide range of industries and everyday activities. Unlike many other organic chemical contaminants that are manufactured and regulated, PAHs continue to be released on a global scale because of the world's dependence on fossil fuels. This chapter briefly reviews the transformation of PAHs in the aquatic environment, highlighting their efficient metabolism in fish and focuses on evidence that links PAH exposure to a wide range of biological dysfunctions in fish. These dysfunctions include neoplasia, reduced reproductive success and other types of endocrine disruption, immunotoxicity, postlarval growth and somatic condition, transgenerational impacts, and finally, recent findings showing that the embryonic development of fish is severely affected by extremely low concentrations of PAH exposure. A brief review of the effects of naphthenic acids on fish is also included because these compounds are increasingly recognized as major factors in the toxicity of process waters from a variety of petroleum sources, most notably the immense oil sands deposits found in Alberta, Canada. It is recommended that future research for understanding and mitigating the effects of PAHs in fish and associated aquatic ecosytems should include the following. Using models to link molecular-up-to-organismal level effects to population-relevant metrics. Building on current case studies demonstrating the effects of PAHs on the health of fish in their natural environments in order to derive regulatory approaches. Current approaches that rely on biota to sediment accumulation factors (BSAF) will not work with contaminants that are efficiently metabolized by species of concern. Focusing considerable resources on better analytical chemistry for both PAHs and naphthenic acids. Currently, our ability to understand and mitigate the effects of these substances is heavily limited by constraints in analysis." @default.
• W189616045 created "2016-06-24" @default.
• W189616045 creator A5002591497 @default.
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• W189616045 creator A5059289971 @default.
• W189616045 creator A5067631894 @default.
• W189616045 date "2013-01-01" @default.
• W189616045 modified "2023-10-04" @default.
• W189616045 title "Effects on Fish of Polycyclic Aromatic HydrocarbonS (PAHS) and Naphthenic Acid Exposures" @default.
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