FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1897433911> ?p ?o ?g. }

• W1897433911 endingPage "6820" @default.
• W1897433911 startingPage "6814" @default.
• W1897433911 abstract "Recent studies have defined vaccinia virus (VACV)-specific CD8(+) T cell epitopes in mice and humans. However, little is known about the epitope specificities of CD4(+) T cell responses. In this study, we identified 14 I-A(b)-restricted VACV-specific CD4(+) T cell epitopes by screening a large set of 2146 different 15-mer peptides in C57BL/6 mice. These epitopes account for approximately 20% of the total anti-VACV CD4(+) T cell response and are derived from 13 different viral proteins. Surprisingly, none of the CD4(+) T cell epitopes identified was derived from VACV virulence factors. Although early Ags were recognized, late Ags predominated as CD4(+) T cell targets. These results are in contrast to what was previously found in CD8(+) T cells responses, where early Ags, including virulence factors, were prominently recognized. Taken together, these results highlight fundamental differences in immunodominance of CD4(+) and CD8(+) T cell responses to a complex pathogen." @default.
• W1897433911 created "2016-06-24" @default.
• W1897433911 creator A5010966529 @default.
• W1897433911 creator A5013760474 @default.
• W1897433911 creator A5023547268 @default.
• W1897433911 creator A5026083514 @default.
• W1897433911 creator A5026809420 @default.
• W1897433911 creator A5030160770 @default.
• W1897433911 creator A5036973489 @default.
• W1897433911 creator A5037285448 @default.
• W1897433911 creator A5060860013 @default.
• W1897433911 creator A5072375249 @default.
• W1897433911 creator A5076329672 @default.
• W1897433911 creator A5079561906 @default.
• W1897433911 date "2007-05-18" @default.
• W1897433911 modified "2023-10-16" @default.
• W1897433911 title "Vaccinia Virus-Specific CD4⁺T Cell Responses Target a Set of Antigens Largely Distinct from Those Targeted by CD8⁺T Cell Responses" @default.
• W1897433911 cites W1493822493 @default.
• W1897433911 cites W1521591765 @default.
• W1897433911 cites W1538962595 @default.
• W1897433911 cites W1553821274 @default.
• W1897433911 cites W1588460910 @default.
• W1897433911 cites W1603918837 @default.
• W1897433911 cites W1661544713 @default.
• W1897433911 cites W1900201877 @default.
• W1897433911 cites W1966505472 @default.
• W1897433911 cites W1977189837 @default.
• W1897433911 cites W1977739694 @default.
• W1897433911 cites W2004764054 @default.
• W1897433911 cites W2008667095 @default.
• W1897433911 cites W2019711015 @default.
• W1897433911 cites W2073254456 @default.
• W1897433911 cites W2073551846 @default.
• W1897433911 cites W2075921307 @default.
• W1897433911 cites W2094968966 @default.
• W1897433911 cites W2096620145 @default.
• W1897433911 cites W2100170686 @default.
• W1897433911 cites W2103849595 @default.
• W1897433911 cites W2106660753 @default.
• W1897433911 cites W2107201675 @default.
• W1897433911 cites W2110379511 @default.
• W1897433911 cites W2118071875 @default.
• W1897433911 cites W2120728534 @default.
• W1897433911 cites W2121192317 @default.
• W1897433911 cites W2123052625 @default.
• W1897433911 cites W2131748930 @default.
• W1897433911 cites W2134161715 @default.
• W1897433911 cites W2137940095 @default.
• W1897433911 cites W2143333377 @default.
• W1897433911 cites W2147673540 @default.
• W1897433911 cites W2149630164 @default.
• W1897433911 cites W2152245700 @default.
• W1897433911 cites W2157995390 @default.
• W1897433911 cites W2160885488 @default.
• W1897433911 cites W2166213347 @default.
• W1897433911 cites W2166852908 @default.
• W1897433911 cites W2168122647 @default.
• W1897433911 cites W2169455131 @default.
• W1897433911 cites W2170303456 @default.
• W1897433911 doi "https://doi.org/10.4049/jimmunol.178.11.6814" @default.
• W1897433911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17513729" @default.
• W1897433911 hasPublicationYear "2007" @default.
• W1897433911 type Work @default.
• W1897433911 sameAs 1897433911 @default.
• W1897433911 citedByCount "99" @default.
• W1897433911 countsByYear W18974339112012 @default.
• W1897433911 countsByYear W18974339112013 @default.
• W1897433911 countsByYear W18974339112014 @default.
• W1897433911 countsByYear W18974339112015 @default.
• W1897433911 countsByYear W18974339112016 @default.
• W1897433911 countsByYear W18974339112017 @default.
• W1897433911 countsByYear W18974339112018 @default.
• W1897433911 countsByYear W18974339112019 @default.
• W1897433911 countsByYear W18974339112020 @default.
• W1897433911 countsByYear W18974339112021 @default.
• W1897433911 countsByYear W18974339112022 @default.
• W1897433911 countsByYear W18974339112023 @default.
• W1897433911 crossrefType "journal-article" @default.
• W1897433911 hasAuthorship W1897433911A5010966529 @default.
• W1897433911 hasAuthorship W1897433911A5013760474 @default.
• W1897433911 hasAuthorship W1897433911A5023547268 @default.
• W1897433911 hasAuthorship W1897433911A5026083514 @default.
• W1897433911 hasAuthorship W1897433911A5026809420 @default.
• W1897433911 hasAuthorship W1897433911A5030160770 @default.
• W1897433911 hasAuthorship W1897433911A5036973489 @default.
• W1897433911 hasAuthorship W1897433911A5037285448 @default.
• W1897433911 hasAuthorship W1897433911A5060860013 @default.
• W1897433911 hasAuthorship W1897433911A5072375249 @default.
• W1897433911 hasAuthorship W1897433911A5076329672 @default.
• W1897433911 hasAuthorship W1897433911A5079561906 @default.
• W1897433911 hasBestOaLocation W18974339111 @default.
• W1897433911 hasConcept C104317684 @default.
• W1897433911 hasConcept C147483822 @default.
• W1897433911 hasConcept C154317977 @default.
• W1897433911 hasConcept C159047783 @default.
• W1897433911 hasConcept C167672396 @default.
• W1897433911 hasConcept C195616568 @default.
• W1897433911 hasConcept C202751555 @default.

• next