Matches in SemOpenAlex for { <https://semopenalex.org/work/W1897472934> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W1897472934 endingPage "1082" @default.
- W1897472934 startingPage "1079" @default.
- W1897472934 abstract "Abstract Aim: Recent research suggests that genetic variance determining the strength of noradrenergic transmitting might contribute to the aetiology of SIDS. We have typed 2 functional polymorphisms of relevance for both biosynthesis and catabolism of noradrenalin: The Val158Met single‐nucleotide polymorphism (SNP) of the Catechol‐ O ‐methyl transferase gene (COMT) and the 1021C/T SNP of the dopamine dehydroxylase gene (DBH). Methods: COMT and DBH were typed in 171 and 196 SIDS cases and 213 and 244 controls, respectively, using PCR followed by digestion with restriction enzymes. Typing was performed using a QIAxcel automatic electrophoresis unit. Results: Both SNPs were in Hardy–Weinberg equilibrium, and for none of these polymorphisms, an association with SIDS could be demonstrated. The allelic frequencies of the DBH locus were C: 78.32% and T: 21.68% in SIDS and C: 77.66% and T: 22.34% in controls. For the COMT locus, the allelic frequencies were A: 51.17% and G: 48.83% in SIDS and A: 52.82% and G: 47.18% in controls. Conclusion: Despite these negative results, the noradrenergic system is still an attractive candidate as modulator of SIDS risk to our eyes. There are several genes involved in this system that have not been studied up to now." @default.
- W1897472934 created "2016-06-24" @default.
- W1897472934 creator A5040766812 @default.
- W1897472934 creator A5060408971 @default.
- W1897472934 date "2012-07-10" @default.
- W1897472934 modified "2023-10-18" @default.
- W1897472934 title "No association of SIDS with two polymorphisms in genes relevant for the noradrenergic system: COMT and DBH" @default.
- W1897472934 cites W1974135788 @default.
- W1897472934 cites W1974504450 @default.
- W1897472934 cites W1978841397 @default.
- W1897472934 cites W2009041906 @default.
- W1897472934 cites W2014218720 @default.
- W1897472934 cites W2029900977 @default.
- W1897472934 cites W2034349712 @default.
- W1897472934 cites W2041540377 @default.
- W1897472934 cites W2047173871 @default.
- W1897472934 cites W2052554098 @default.
- W1897472934 cites W2060696915 @default.
- W1897472934 cites W2065090972 @default.
- W1897472934 cites W2070533285 @default.
- W1897472934 cites W2088708198 @default.
- W1897472934 cites W2100040984 @default.
- W1897472934 cites W2104671291 @default.
- W1897472934 cites W2108710130 @default.
- W1897472934 cites W2119243552 @default.
- W1897472934 cites W2120750686 @default.
- W1897472934 cites W2129696659 @default.
- W1897472934 cites W2144491752 @default.
- W1897472934 cites W2157704351 @default.
- W1897472934 cites W2171477850 @default.
- W1897472934 doi "https://doi.org/10.1111/j.1651-2227.2012.02764.x" @default.
- W1897472934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22765285" @default.
- W1897472934 hasPublicationYear "2012" @default.
- W1897472934 type Work @default.
- W1897472934 sameAs 1897472934 @default.
- W1897472934 citedByCount "6" @default.
- W1897472934 countsByYear W18974729342013 @default.
- W1897472934 countsByYear W18974729342014 @default.
- W1897472934 countsByYear W18974729342015 @default.
- W1897472934 countsByYear W18974729342021 @default.
- W1897472934 crossrefType "journal-article" @default.
- W1897472934 hasAuthorship W1897472934A5040766812 @default.
- W1897472934 hasAuthorship W1897472934A5060408971 @default.
- W1897472934 hasConcept C104317684 @default.
- W1897472934 hasConcept C126322002 @default.
- W1897472934 hasConcept C135763542 @default.
- W1897472934 hasConcept C139275648 @default.
- W1897472934 hasConcept C153209595 @default.
- W1897472934 hasConcept C180754005 @default.
- W1897472934 hasConcept C185361966 @default.
- W1897472934 hasConcept C186413461 @default.
- W1897472934 hasConcept C37463918 @default.
- W1897472934 hasConcept C54355233 @default.
- W1897472934 hasConcept C71924100 @default.
- W1897472934 hasConcept C84597430 @default.
- W1897472934 hasConcept C86803240 @default.
- W1897472934 hasConceptScore W1897472934C104317684 @default.
- W1897472934 hasConceptScore W1897472934C126322002 @default.
- W1897472934 hasConceptScore W1897472934C135763542 @default.
- W1897472934 hasConceptScore W1897472934C139275648 @default.
- W1897472934 hasConceptScore W1897472934C153209595 @default.
- W1897472934 hasConceptScore W1897472934C180754005 @default.
- W1897472934 hasConceptScore W1897472934C185361966 @default.
- W1897472934 hasConceptScore W1897472934C186413461 @default.
- W1897472934 hasConceptScore W1897472934C37463918 @default.
- W1897472934 hasConceptScore W1897472934C54355233 @default.
- W1897472934 hasConceptScore W1897472934C71924100 @default.
- W1897472934 hasConceptScore W1897472934C84597430 @default.
- W1897472934 hasConceptScore W1897472934C86803240 @default.
- W1897472934 hasIssue "10" @default.
- W1897472934 hasLocation W18974729341 @default.
- W1897472934 hasLocation W18974729342 @default.
- W1897472934 hasOpenAccess W1897472934 @default.
- W1897472934 hasPrimaryLocation W18974729341 @default.
- W1897472934 hasRelatedWork W100326482 @default.
- W1897472934 hasRelatedWork W1587862541 @default.
- W1897472934 hasRelatedWork W1601337698 @default.
- W1897472934 hasRelatedWork W1972273317 @default.
- W1897472934 hasRelatedWork W1987313132 @default.
- W1897472934 hasRelatedWork W2009457246 @default.
- W1897472934 hasRelatedWork W2488066419 @default.
- W1897472934 hasRelatedWork W2507661118 @default.
- W1897472934 hasRelatedWork W3132297604 @default.
- W1897472934 hasRelatedWork W4254462449 @default.
- W1897472934 hasVolume "101" @default.
- W1897472934 isParatext "false" @default.
- W1897472934 isRetracted "false" @default.
- W1897472934 magId "1897472934" @default.
- W1897472934 workType "article" @default.