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• W1897655817 abstract "The purpose was to evaluate and correct the co-registration of diagnostic PET/CT and MRI/MRI images for stereotactic radiosurgery (SRS) using 3D volumetric image registration (3DVIR). The 3DVIR utilizes the homogeneity of color distribution over a volumetric anatomical landmark as the registration criterion with submillimeter accuracy. Fifty-three PET/CT and MRI (T1, T2 and FLAIR) image sets of patients with brain lesions were acquired sequentially from a hybrid PET/CT or an MRI scanner with common diagnostic head holding devices. Twenty-five sets of head images were scanned over a 10-minute interval and 14 whole-body sets were scanned over a 30-minute interval. Fourteen sets of MRI images were acquired, and each 3-modal image set (T1, T2 and FLAIR) was scanned in sequence at time 0, and minutes. The misalignments in these “co-registered” images were evaluated and corrected using the 3DVIR. Using the head immobilization devices commonly found in diagnostic PET/CT and MRI/MRI imaging, 80%–100% of these “co-registered” images were identified as misaligned. For PET/CT, the magnitude of misalignment was and for 10-minute scans, and and for 30-minute scans. For MRI/MRI, the magnitude was and for 5-minute scan intervals, and and for 20-minute intervals. Small, but significant, misalignment is present in the co-registered diagnostic PET/CT and MRI/MRI images and can be corrected in SRS treatment planning using the volumetric image registration for improved target localization within the clinical error tolerance. PACS numbers: 87.53.Ly, 87.57.nj, 87.57.uk, 87.57.Q-, 87.61.jc, 87.19.xc Conflict of Interest Statement: The authors do not have any conflict of interest on this research report." @default.
• W1897655817 created "2016-06-24" @default.
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• W1897655817 date "2010-10-07" @default.
• W1897655817 modified "2023-10-16" @default.
• W1897655817 title "Correction of motion-induced misalignment in co-registered PET/CT and MRI (T1/T2/FLAIR) head images for stereotactic radiosurgery" @default.
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• W1897655817 doi "https://doi.org/10.1120/jacmp.v12i1.3306" @default.
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