FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1898350887> ?p ?o ?g. }

• W1898350887 endingPage "520" @default.
• W1898350887 startingPage "514" @default.
• W1898350887 abstract "A recombinant Borrelia burgdorferi flagellin protein expressed in Escherichia coli is bound by a murine monoclonal antiflagellin antibody (H9724) and by antibodies in the sera of patients with Lyme disease. Immunoreactive epitopes on the flagellar protein were identified by immunoblot analysis of antibody binding to expressed truncated flagellar proteins. The epitope recognized by the murine monoclonal antibody is within the central heterologous region of the flagellar protein (amino acids 90 to 266). However, antiflagellin antibodies in the sera of patients with Lyme arthritis bound an epitope entirely within, or whose conformation was partly formed by, the 90 NH2-terminal amino acids of the flagellar protein. The binding of antibodies in the sera of patients with Lyme arthritis to the NH2-terminal region of the flagellar protein, a region with sequence homology to the flagellar proteins of other bacterial species, suggests the possibility that antigenic mimicry contributes to the immunopathogenesis of Lyme disease. The fact that human antibodies bind to a highly conserved and hence shared portion of the flagellin reduces the specificity of serological assays for the diagnosis of Lyme disease which use the flagellar protein as antigen." @default.
• W1898350887 created "2016-06-24" @default.
• W1898350887 creator A5002497252 @default.
• W1898350887 creator A5016419819 @default.
• W1898350887 date "1991-02-01" @default.
• W1898350887 modified "2023-09-25" @default.
• W1898350887 title "Immunoreactive epitopes on an expressed recombinant flagellar protein of Borrelia burgdorferi" @default.
• W1898350887 cites W1545483534 @default.
• W1898350887 cites W1621593382 @default.
• W1898350887 cites W1701714503 @default.
• W1898350887 cites W1847119553 @default.
• W1898350887 cites W1848367183 @default.
• W1898350887 cites W1902145916 @default.
• W1898350887 cites W1912214366 @default.
• W1898350887 cites W1939198725 @default.
• W1898350887 cites W1974567944 @default.
• W1898350887 cites W1990204841 @default.
• W1898350887 cites W2015028668 @default.
• W1898350887 cites W2020184986 @default.
• W1898350887 cites W2020380359 @default.
• W1898350887 cites W2052662005 @default.
• W1898350887 cites W2060333964 @default.
• W1898350887 cites W2063367477 @default.
• W1898350887 cites W2072246068 @default.
• W1898350887 cites W2074454643 @default.
• W1898350887 cites W2076721603 @default.
• W1898350887 cites W2120521437 @default.
• W1898350887 cites W2123010258 @default.
• W1898350887 cites W2127962377 @default.
• W1898350887 cites W2166236008 @default.
• W1898350887 cites W2175467747 @default.
• W1898350887 cites W36295273 @default.
• W1898350887 doi "https://doi.org/10.1128/iai.59.2.514-520.1991" @default.
• W1898350887 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/257779" @default.
• W1898350887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1702766" @default.
• W1898350887 hasPublicationYear "1991" @default.
• W1898350887 type Work @default.
• W1898350887 sameAs 1898350887 @default.
• W1898350887 citedByCount "30" @default.
• W1898350887 countsByYear W18983508872015 @default.
• W1898350887 countsByYear W18983508872023 @default.
• W1898350887 crossrefType "journal-article" @default.
• W1898350887 hasAuthorship W1898350887A5002497252 @default.
• W1898350887 hasAuthorship W1898350887A5016419819 @default.
• W1898350887 hasBestOaLocation W18983508871 @default.
• W1898350887 hasConcept C104317684 @default.
• W1898350887 hasConcept C147483822 @default.
• W1898350887 hasConcept C153911025 @default.
• W1898350887 hasConcept C159047783 @default.
• W1898350887 hasConcept C159654299 @default.
• W1898350887 hasConcept C167625842 @default.
• W1898350887 hasConcept C195616568 @default.
• W1898350887 hasConcept C203014093 @default.
• W1898350887 hasConcept C2777119779 @default.
• W1898350887 hasConcept C2777553296 @default.
• W1898350887 hasConcept C2779026604 @default.
• W1898350887 hasConcept C2779159148 @default.
• W1898350887 hasConcept C2780508971 @default.
• W1898350887 hasConcept C2780632150 @default.
• W1898350887 hasConcept C2781241564 @default.
• W1898350887 hasConcept C38117629 @default.
• W1898350887 hasConcept C40767141 @default.
• W1898350887 hasConcept C523546767 @default.
• W1898350887 hasConcept C542903549 @default.
• W1898350887 hasConcept C54355233 @default.
• W1898350887 hasConcept C55493867 @default.
• W1898350887 hasConcept C86803240 @default.
• W1898350887 hasConcept C89423630 @default.
• W1898350887 hasConceptScore W1898350887C104317684 @default.
• W1898350887 hasConceptScore W1898350887C147483822 @default.
• W1898350887 hasConceptScore W1898350887C153911025 @default.
• W1898350887 hasConceptScore W1898350887C159047783 @default.
• W1898350887 hasConceptScore W1898350887C159654299 @default.
• W1898350887 hasConceptScore W1898350887C167625842 @default.
• W1898350887 hasConceptScore W1898350887C195616568 @default.
• W1898350887 hasConceptScore W1898350887C203014093 @default.
• W1898350887 hasConceptScore W1898350887C2777119779 @default.
• W1898350887 hasConceptScore W1898350887C2777553296 @default.
• W1898350887 hasConceptScore W1898350887C2779026604 @default.
• W1898350887 hasConceptScore W1898350887C2779159148 @default.
• W1898350887 hasConceptScore W1898350887C2780508971 @default.
• W1898350887 hasConceptScore W1898350887C2780632150 @default.
• W1898350887 hasConceptScore W1898350887C2781241564 @default.
• W1898350887 hasConceptScore W1898350887C38117629 @default.
• W1898350887 hasConceptScore W1898350887C40767141 @default.
• W1898350887 hasConceptScore W1898350887C523546767 @default.
• W1898350887 hasConceptScore W1898350887C542903549 @default.
• W1898350887 hasConceptScore W1898350887C54355233 @default.
• W1898350887 hasConceptScore W1898350887C55493867 @default.
• W1898350887 hasConceptScore W1898350887C86803240 @default.
• W1898350887 hasConceptScore W1898350887C89423630 @default.
• W1898350887 hasIssue "2" @default.
• W1898350887 hasLocation W18983508871 @default.
• W1898350887 hasLocation W18983508872 @default.
• W1898350887 hasOpenAccess W1898350887 @default.
• W1898350887 hasPrimaryLocation W18983508871 @default.
• W1898350887 hasRelatedWork W1704050937 @default.
• W1898350887 hasRelatedWork W1898350887 @default.

• next