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• W1899976422 abstract "Multiple sclerosis (MS) is a chronic, progressive, and disabling disease of the central nervous system with dramatic variations in the combination and severity of symptoms it can produce. The lack of reliable disease-specific health-related quality of life (HRQL) measures for use in clinical trials prompted the development of the Neurology Quality of Life (Neuro-QOL) instrument, which includes 13 scales that assess physical, emotional, cognitive, and social domains, for use in a variety of neurological illnesses.The objective of this research paper is to conduct an initial assessment of the reliability and validation of the Neuro-QOL short forms (SFs) in MS.We assessed reliability, concurrent validity, known groups validity, and responsiveness between cross-sectional and longitudinal data in 161 recruited MS patients.Internal consistency was high for all measures (α = 0.81-0.95) and ICCs were within the acceptable range (0.76-0.91); concurrent and known groups validity were highest with the Global HRQL question. Longitudinal assessment was limited by the lack of disease progression in the group.The Neuro-QOL SFs demonstrate good internal consistency, test-re-test reliability, and concurrent and known groups validity in this MS population, supporting the validity of Neuro-QOL in adults with MS." @default.
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• W1899976422 date "2015-08-03" @default.
• W1899976422 modified "2023-10-03" @default.
• W1899976422 title "Validating Neuro-QoL short forms and targeted scales with people who have multiple sclerosis" @default.
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• W1899976422 doi "https://doi.org/10.1177/1352458515599450" @default.
• W1899976422 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4740288" @default.
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