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- W1900103553 abstract "Microsporidial myositis is a rare opportunistic infection that has been reported in HIV-infected and HIV-uninfected immunocompromised patients.In this study we present a retrospective analysis of 5 cases of microsporidial myositis in HIV-infected patients, including the clinical, laboratory, and histologic features, and a review of the literature.Five young men with HIV infection [median CD4 count of 20 cells (range 14-144)/mm(3) ] who presented with signs and symptoms suggestive of myositis underwent EMG-NCV and muscle biopsy, which revealed signs compatible with microsporidial myositis. Early and aggressive treatment led to improvement in 3 patients. Two of the 5 patients died due to a delay in diagnosis, because the spores were mistaken for Candida without confirmatory stains or a high index of suspicion.Myositis in HIV-infected patients with low CD4 counts should be evaluated using muscle biopsy. A high index of suspicion is required for early diagnosis of microsporidial myositis in HIV-infected patients. Early diagnosis and immediate, aggressive treatment are the keys to favorable outcomes in these patients." @default.
- W1900103553 created "2016-06-24" @default.
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- W1900103553 date "2015-02-11" @default.
- W1900103553 modified "2023-10-05" @default.
- W1900103553 title "Microsporidial polymyositis in human immunodeficiency virus−infected patients, a rare life-threatening opportunistic infection: Clinical suspicion, diagnosis, and management in resource-limited settings" @default.
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- W1900103553 doi "https://doi.org/10.1002/mus.24513" @default.
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