FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1900107061> ?p ?o ?g. }

• W1900107061 endingPage "27" @default.
• W1900107061 startingPage "15" @default.
• W1900107061 abstract "Abstract Inherent pathologies associated with diabetic wound microenvironment including increased proteolysis, inflammatory dysregulation, and impaired neovascularization prevent timely resolution of chronic diabetic ulcers. It is hypothesized that augmentation of local wound microenvironment with a stable provisional matrix formed by proteolysis‐resistant angiogenic peptide nanofibers ( NFs ) will create permissive environment for attenuated inflammation, enhanced neovascularization, and improved diabetic wound healing. Using murine excisional wound healing models, full‐thickness dorsal skin wounds were treated with either NFs or control solutions (phosphate buffered saline; hyaluronic acid) and analyzed for morphology, inflammatory response, neovascularization, and biomechanical properties. NF treatment of diabetic wounds stimulated formation of a robust pro‐angiogenic in situ tissue‐engineered provisional matrix leading to a significant decrease in wound inflammatory cell infiltration and proinflammatory interleukin‐6 levels, a significant increase in endothelial and endothelial progenitor cell infiltration, vascular endothelial growth factor levels, and neovascularization (day 7), as well as improved wound morphology, accelerated wound closure, and significantly stronger repair tissue (day 28). These results suggest that appropriate design of provisional matrix may compensate for some of the complex disruptions in diabetic wound microenvironment and provide missing cues to cells and direct in situ responses toward improved healing, which is promising for future development of new therapies for diabetic ulcers." @default.
• W1900107061 created "2016-06-24" @default.
• W1900107061 creator A5011469997 @default.
• W1900107061 creator A5015563057 @default.
• W1900107061 creator A5037361729 @default.
• W1900107061 creator A5044941877 @default.
• W1900107061 creator A5070887889 @default.
• W1900107061 creator A5076673375 @default.
• W1900107061 creator A5082901450 @default.
• W1900107061 date "2011-12-08" @default.
• W1900107061 modified "2023-10-16" @default.
• W1900107061 title "Tissue-engineered provisional matrix as a novel approach to enhance diabetic wound healing" @default.
• W1900107061 cites W1520623323 @default.
• W1900107061 cites W1577847062 @default.
• W1900107061 cites W1967162280 @default.
• W1900107061 cites W1969592520 @default.
• W1900107061 cites W1969806743 @default.
• W1900107061 cites W1971460749 @default.
• W1900107061 cites W1973895231 @default.
• W1900107061 cites W1978994469 @default.
• W1900107061 cites W1980923037 @default.
• W1900107061 cites W1985861597 @default.
• W1900107061 cites W1989483643 @default.
• W1900107061 cites W2007357135 @default.
• W1900107061 cites W2010819089 @default.
• W1900107061 cites W2012774822 @default.
• W1900107061 cites W2019507287 @default.
• W1900107061 cites W2019567095 @default.
• W1900107061 cites W2025138472 @default.
• W1900107061 cites W2032013289 @default.
• W1900107061 cites W2036173323 @default.
• W1900107061 cites W2037618281 @default.
• W1900107061 cites W2044860512 @default.
• W1900107061 cites W2065942568 @default.
• W1900107061 cites W2065964498 @default.
• W1900107061 cites W2072755205 @default.
• W1900107061 cites W2083062783 @default.
• W1900107061 cites W2087954500 @default.
• W1900107061 cites W2089818317 @default.
• W1900107061 cites W2093969982 @default.
• W1900107061 cites W2098767125 @default.
• W1900107061 cites W2109082151 @default.
• W1900107061 cites W2114736117 @default.
• W1900107061 cites W2115294353 @default.
• W1900107061 cites W2116120286 @default.
• W1900107061 cites W2118373226 @default.
• W1900107061 cites W2120472250 @default.
• W1900107061 cites W2133226946 @default.
• W1900107061 cites W2142041241 @default.
• W1900107061 cites W2143303248 @default.
• W1900107061 cites W2144951006 @default.
• W1900107061 cites W2146580874 @default.
• W1900107061 cites W2149209677 @default.
• W1900107061 cites W2152476796 @default.
• W1900107061 cites W2166637527 @default.
• W1900107061 cites W2168783417 @default.
• W1900107061 cites W59556011 @default.
• W1900107061 doi "https://doi.org/10.1111/j.1524-475x.2011.00750.x" @default.
• W1900107061 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22151855" @default.
• W1900107061 hasPublicationYear "2011" @default.
• W1900107061 type Work @default.
• W1900107061 sameAs 1900107061 @default.
• W1900107061 citedByCount "29" @default.
• W1900107061 countsByYear W19001070612013 @default.
• W1900107061 countsByYear W19001070612014 @default.
• W1900107061 countsByYear W19001070612015 @default.
• W1900107061 countsByYear W19001070612016 @default.
• W1900107061 countsByYear W19001070612019 @default.
• W1900107061 countsByYear W19001070612020 @default.
• W1900107061 countsByYear W19001070612021 @default.
• W1900107061 countsByYear W19001070612022 @default.
• W1900107061 countsByYear W19001070612023 @default.
• W1900107061 crossrefType "journal-article" @default.
• W1900107061 hasAuthorship W1900107061A5011469997 @default.
• W1900107061 hasAuthorship W1900107061A5015563057 @default.
• W1900107061 hasAuthorship W1900107061A5037361729 @default.
• W1900107061 hasAuthorship W1900107061A5044941877 @default.
• W1900107061 hasAuthorship W1900107061A5070887889 @default.
• W1900107061 hasAuthorship W1900107061A5076673375 @default.
• W1900107061 hasAuthorship W1900107061A5082901450 @default.
• W1900107061 hasConcept C105702510 @default.
• W1900107061 hasConcept C141071460 @default.
• W1900107061 hasConcept C164027704 @default.
• W1900107061 hasConcept C167734588 @default.
• W1900107061 hasConcept C203014093 @default.
• W1900107061 hasConcept C2776914184 @default.
• W1900107061 hasConcept C2777025900 @default.
• W1900107061 hasConcept C2777529286 @default.
• W1900107061 hasConcept C2778271429 @default.
• W1900107061 hasConcept C2780269544 @default.
• W1900107061 hasConcept C2780394083 @default.
• W1900107061 hasConcept C502942594 @default.
• W1900107061 hasConcept C71924100 @default.
• W1900107061 hasConceptScore W1900107061C105702510 @default.
• W1900107061 hasConceptScore W1900107061C141071460 @default.
• W1900107061 hasConceptScore W1900107061C164027704 @default.
• W1900107061 hasConceptScore W1900107061C167734588 @default.
• W1900107061 hasConceptScore W1900107061C203014093 @default.

• next