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- W1900525991 abstract "Lung cancer is the most commonly diagnosed cancer as well as the leading cause of cancer death worldwide. Observational studies on the prognostic role of SOX-2 in non-small-cell lung cancer (NSCLC) are controversial.To clarify the impact of SOX-2 in NSCLC survival, we performed this meta-analysis that included eligible studies. The combined hazard ratios and their corresponding 95% confidence intervals (95% CI) were calculated in terms of overall survival.A total of seven studies with 1,944 patients were evaluable for this meta-analysis. The studies were categorized by histology, disease stage and patient race. Our results suggested that SOX-2 overexpression had a favorable impact on survival of patients with NSCLC, the HR (95% CI) was 0.57 (0.48 to 0.65). However, highly significant heterogeneity was detected among these studies (I(2)=76.7%, P=0.000).SOX-2 overexpression indicates a favorable prognosis for patients with NSCLC." @default.
- W1900525991 created "2016-06-24" @default.
- W1900525991 creator A5002973998 @default.
- W1900525991 creator A5015539189 @default.
- W1900525991 creator A5074447759 @default.
- W1900525991 date "2015-07-01" @default.
- W1900525991 modified "2023-10-17" @default.
- W1900525991 title "The role of SOX-2 on the survival of patients with non-small cell lung cancer." @default.
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- W1900525991 doi "https://doi.org/10.3978/j.issn.2072-1439.2015.07.14" @default.
- W1900525991 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4522480" @default.
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