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- W1900780398 abstract "Abstract: Jatropha gossypifolia has been used in Indian traditional system but there is paucity of scientific data on anti-inflammatory activity of root. Anti-inflammatory activity was evaluated by TPA (12- O -tetradecanoylphorbol-13-acetate) induced ear inflammation, carrageenan-induced paw edema and cotton pellet granuloma. Topical application of 0.5 and 1 mg extract significantly reduced the TPA induced ear inflammation. The extract (125 mg/kg p.o) significantly reduced the carrageenan induced edema. Seven days administration of 50 and 100 mg/kg of extract significantly reduced the cotton pellet granuloma. The activity might be due to effects on several mediators involving cyclooxygenase pathway resulting in prostaglandin formation and leukocyte migration." @default.
- W1900780398 created "2016-06-24" @default.
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- W1900780398 date "2013-04-01" @default.
- W1900780398 modified "2023-09-25" @default.
- W1900780398 title "HPTLC analysis and Anti-inflammatory activity of Jatropha gossypifolia L. root in mice and Wistar rats" @default.
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- W1900780398 doi "https://doi.org/10.7439/ijpr.v3i1.36" @default.
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