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- W1900994610 abstract "Atopic dermatitis (AD) is a chronic recurrent disease of childhood. The therapeutics of AD needs to be more tailored given the new cytokine antibodies available. In this scenario we considered interleukin 1 beta (IL-1β) levels before and after therapy with topical corticosteroids.To measure the IL-1β levels before and after treatment in patients with AD after 75% improvement in scoring for atopic dermatitis index.Forty-five subjects with AD were treated with betamethasone ointment and their IL-1β level was measured prior to and following treatment.The IL-1β levels were raised during disease activity and following improvement they decreased in a statistically significant manner. Also the IL-1β levels corresponded with the severity of disease activity.Newer modalities of therapy in the form of cytokine monoclonal antibodies should be studied in a larger scale in AD." @default.
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- W1900994610 date "2011-05-31" @default.
- W1900994610 modified "2023-10-17" @default.
- W1900994610 title "The effect of topically applied corticosteroids on interleukin 1β levels in patients with atopic dermatitis" @default.
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- W1900994610 doi "https://doi.org/10.1111/j.1468-3083.2011.04133.x" @default.
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