Matches in SemOpenAlex for { <https://semopenalex.org/work/W1901050173> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W1901050173 endingPage "1210" @default.
- W1901050173 startingPage "1202" @default.
- W1901050173 abstract "Older donor age is associated with lower graft and patient survival among all recipients of liver transplantation (LT). Among patients with hepatitis C virus (HCV), donor age is one of the strongest predictors of fibrosis severity and graft loss. We evaluated the implementation of a donor age restriction policy for LT patients with HCV at a single center and the effects that this policy had on wait-list (WL) and post-LT outcomes for HCV and non-HCV patients. This was a cohort study of 2388 WL patients and 1015 LT recipients between March 2002 and January 2013 and reflected 3 different eras of donor age policies. With the donor age restriction, the median donor age was reduced in LT recipients with HCV versus LT recipients without HCV (30 versus 48 years, P < 0.001) without differences in the WL time (10.6 versus 8.0 months, P = 0.23). According to a competing risks regression, those with HCV and those without HCV had lower subhazard ratios (SHRs) of dropout or death on the WL during the donor age restriction era versus the era without donor age restriction [SHR = 0.68 (P < 0.01) and SHR = 0.64 (P = 0.01), respectively]. No differences were seen in early post-LT survival for patients with or without HCV between eras (P = 0.7 and P = 0.88, respectively). In conclusion, we show that donor age restriction for HCV results in a lower donor age for HCV recipients without obvious adverse WL consequences. Although additional studies are needed, our results demonstrate the feasibility of donor age restriction for LT recipients with HCV, and such information may be relevant to programs with limited access to new antiviral therapies for which modifying the risk of severe disease remains of paramount importance." @default.
- W1901050173 created "2016-06-24" @default.
- W1901050173 creator A5013555370 @default.
- W1901050173 creator A5019470247 @default.
- W1901050173 creator A5020853710 @default.
- W1901050173 creator A5024111883 @default.
- W1901050173 creator A5065771539 @default.
- W1901050173 date "2014-09-03" @default.
- W1901050173 modified "2023-10-18" @default.
- W1901050173 title "Restricting liver transplant recipients to younger donors does not increase the wait-list time or the dropout rate: The hepatitis C experience" @default.
- W1901050173 cites W1966112709 @default.
- W1901050173 cites W1978428649 @default.
- W1901050173 cites W1999493138 @default.
- W1901050173 cites W2000845230 @default.
- W1901050173 cites W2025887943 @default.
- W1901050173 cites W2027490560 @default.
- W1901050173 cites W2033560342 @default.
- W1901050173 cites W2033845944 @default.
- W1901050173 cites W2038981426 @default.
- W1901050173 cites W2042158802 @default.
- W1901050173 cites W2045838757 @default.
- W1901050173 cites W2065990825 @default.
- W1901050173 cites W2066166241 @default.
- W1901050173 cites W2074585008 @default.
- W1901050173 cites W2084428065 @default.
- W1901050173 cites W2132328659 @default.
- W1901050173 cites W2136890362 @default.
- W1901050173 cites W2161689638 @default.
- W1901050173 cites W2915588212 @default.
- W1901050173 doi "https://doi.org/10.1002/lt.23937" @default.
- W1901050173 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4803440" @default.
- W1901050173 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24961679" @default.
- W1901050173 hasPublicationYear "2014" @default.
- W1901050173 type Work @default.
- W1901050173 sameAs 1901050173 @default.
- W1901050173 citedByCount "3" @default.
- W1901050173 countsByYear W19010501732015 @default.
- W1901050173 countsByYear W19010501732016 @default.
- W1901050173 crossrefType "journal-article" @default.
- W1901050173 hasAuthorship W1901050173A5013555370 @default.
- W1901050173 hasAuthorship W1901050173A5019470247 @default.
- W1901050173 hasAuthorship W1901050173A5020853710 @default.
- W1901050173 hasAuthorship W1901050173A5024111883 @default.
- W1901050173 hasAuthorship W1901050173A5065771539 @default.
- W1901050173 hasBestOaLocation W19010501731 @default.
- W1901050173 hasConcept C126322002 @default.
- W1901050173 hasConcept C203014093 @default.
- W1901050173 hasConcept C2522874641 @default.
- W1901050173 hasConcept C2776408679 @default.
- W1901050173 hasConcept C2776455275 @default.
- W1901050173 hasConcept C2779609443 @default.
- W1901050173 hasConcept C2911091166 @default.
- W1901050173 hasConcept C71924100 @default.
- W1901050173 hasConcept C72563966 @default.
- W1901050173 hasConcept C90924648 @default.
- W1901050173 hasConceptScore W1901050173C126322002 @default.
- W1901050173 hasConceptScore W1901050173C203014093 @default.
- W1901050173 hasConceptScore W1901050173C2522874641 @default.
- W1901050173 hasConceptScore W1901050173C2776408679 @default.
- W1901050173 hasConceptScore W1901050173C2776455275 @default.
- W1901050173 hasConceptScore W1901050173C2779609443 @default.
- W1901050173 hasConceptScore W1901050173C2911091166 @default.
- W1901050173 hasConceptScore W1901050173C71924100 @default.
- W1901050173 hasConceptScore W1901050173C72563966 @default.
- W1901050173 hasConceptScore W1901050173C90924648 @default.
- W1901050173 hasIssue "10" @default.
- W1901050173 hasLocation W19010501731 @default.
- W1901050173 hasLocation W19010501732 @default.
- W1901050173 hasLocation W19010501733 @default.
- W1901050173 hasLocation W19010501734 @default.
- W1901050173 hasLocation W19010501735 @default.
- W1901050173 hasOpenAccess W1901050173 @default.
- W1901050173 hasPrimaryLocation W19010501731 @default.
- W1901050173 hasRelatedWork W1481987224 @default.
- W1901050173 hasRelatedWork W1963598722 @default.
- W1901050173 hasRelatedWork W2000219589 @default.
- W1901050173 hasRelatedWork W2053096801 @default.
- W1901050173 hasRelatedWork W2068802639 @default.
- W1901050173 hasRelatedWork W2126956071 @default.
- W1901050173 hasRelatedWork W2152944181 @default.
- W1901050173 hasRelatedWork W2365865549 @default.
- W1901050173 hasRelatedWork W2774747249 @default.
- W1901050173 hasRelatedWork W3136177459 @default.
- W1901050173 hasVolume "20" @default.
- W1901050173 isParatext "false" @default.
- W1901050173 isRetracted "false" @default.
- W1901050173 magId "1901050173" @default.
- W1901050173 workType "article" @default.