Matches in SemOpenAlex for { <https://semopenalex.org/work/W1901752977> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W1901752977 endingPage "526" @default.
- W1901752977 startingPage "526" @default.
- W1901752977 abstract "The main symptom of osteoarthritis (OA) is pain. Mechanisms of chronic pain in OA have not been fully investigated yet. Objective: to study key mechanisms of chronic pain in patients with knee OA. Subjects and methods. Authors examined 80 women aged 45–65 years, with chronic pain due to OA of the knee. Clinical rheumatologic and neurologic examinations, screening for neuropathic pain (PainDETECT and DN4 questionnaires), estimation of duration and intensity of pain, WOMAC assessment and evaluation of affective disorders (HADS questionnaire) were performed. X-ray and ultrasonography were used to assess destructive changes of the knee. Results. According to DN4 questionnaire, 25 (30%) patients scored 4 and more, i. e. had signs of neuropathic pain, whereas 55 (70%) did not (scored less than 4). Although neurologic examination did not reveal lesions of somatosensory system in neither of groups, assessment of the pain sensitivity showed hyperalgesia in 60% of cases. Patients with signs of neuropathic pain typically have secondary hyperalgesia propagating far from the damaged joint. Conclusion. 30% of patients with osteoarthritis have pain of different intensity determined by nociceptive and neuropathic mechanisms. At the same time the absence of lesions of somatosensory system does not let us to consider the pain neuropathic and indicates that it has dysfunctional nature. Signs of neuropathic pain associated with secondary hyperalgesia may be a clinical symptom of central sensitization. Due to this fact, reasonable therapy of osteoarthritis-associated chronic pain should include, besides NSAIDs, central acting drugs for neuropathic pain treatment." @default.
- W1901752977 created "2016-06-24" @default.
- W1901752977 creator A5008401244 @default.
- W1901752977 creator A5066139129 @default.
- W1901752977 creator A5067928225 @default.
- W1901752977 date "2014-10-07" @default.
- W1901752977 modified "2023-10-01" @default.
- W1901752977 title "MECHANISMS OF CHRONIC PAIN AT OSTEOARTHROSIS OF THE KNEE" @default.
- W1901752977 cites W2061029035 @default.
- W1901752977 cites W2095108162 @default.
- W1901752977 cites W2110591502 @default.
- W1901752977 cites W2113115269 @default.
- W1901752977 cites W2167613032 @default.
- W1901752977 doi "https://doi.org/10.14412/1995-4484-2014-526-529" @default.
- W1901752977 hasPublicationYear "2014" @default.
- W1901752977 type Work @default.
- W1901752977 sameAs 1901752977 @default.
- W1901752977 citedByCount "4" @default.
- W1901752977 countsByYear W19017529772017 @default.
- W1901752977 countsByYear W19017529772018 @default.
- W1901752977 countsByYear W19017529772020 @default.
- W1901752977 countsByYear W19017529772023 @default.
- W1901752977 crossrefType "journal-article" @default.
- W1901752977 hasAuthorship W1901752977A5008401244 @default.
- W1901752977 hasAuthorship W1901752977A5066139129 @default.
- W1901752977 hasAuthorship W1901752977A5067928225 @default.
- W1901752977 hasBestOaLocation W19017529771 @default.
- W1901752977 hasConcept C141071460 @default.
- W1901752977 hasConcept C142724271 @default.
- W1901752977 hasConcept C1862650 @default.
- W1901752977 hasConcept C204787440 @default.
- W1901752977 hasConcept C2776164576 @default.
- W1901752977 hasConcept C2779279471 @default.
- W1901752977 hasConcept C2781118164 @default.
- W1901752977 hasConcept C2908736133 @default.
- W1901752977 hasConcept C71924100 @default.
- W1901752977 hasConcept C99508421 @default.
- W1901752977 hasConceptScore W1901752977C141071460 @default.
- W1901752977 hasConceptScore W1901752977C142724271 @default.
- W1901752977 hasConceptScore W1901752977C1862650 @default.
- W1901752977 hasConceptScore W1901752977C204787440 @default.
- W1901752977 hasConceptScore W1901752977C2776164576 @default.
- W1901752977 hasConceptScore W1901752977C2779279471 @default.
- W1901752977 hasConceptScore W1901752977C2781118164 @default.
- W1901752977 hasConceptScore W1901752977C2908736133 @default.
- W1901752977 hasConceptScore W1901752977C71924100 @default.
- W1901752977 hasConceptScore W1901752977C99508421 @default.
- W1901752977 hasIssue "5" @default.
- W1901752977 hasLocation W19017529771 @default.
- W1901752977 hasLocation W19017529772 @default.
- W1901752977 hasOpenAccess W1901752977 @default.
- W1901752977 hasPrimaryLocation W19017529771 @default.
- W1901752977 hasRelatedWork W2108284278 @default.
- W1901752977 hasRelatedWork W2144200965 @default.
- W1901752977 hasRelatedWork W2145459071 @default.
- W1901752977 hasRelatedWork W2145608536 @default.
- W1901752977 hasRelatedWork W2187766388 @default.
- W1901752977 hasRelatedWork W2314638994 @default.
- W1901752977 hasRelatedWork W2511942257 @default.
- W1901752977 hasRelatedWork W3086760508 @default.
- W1901752977 hasRelatedWork W4324142214 @default.
- W1901752977 hasRelatedWork W2291047949 @default.
- W1901752977 hasVolume "0" @default.
- W1901752977 isParatext "false" @default.
- W1901752977 isRetracted "false" @default.
- W1901752977 magId "1901752977" @default.
- W1901752977 workType "article" @default.