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- W1903019968 abstract "We investigated the rates of expression of bone morphogenetic protein-2 (BMP-2) in 29 adult patients with high-grade malignant fibrous histiocytoma of soft tissue, using the BMP-2-specific monoclonal antibody, AbH3b2/17, and found that they ranged from 1.9% to 78.9%. The survival at five years of the groups expressing high (≥30%) and low (< 30%) levels of BMP-2 was 85.7% and 36.3%, respectively. Multivariable analysis showed that only BMP-2 had prognostic significance for continuous disease-free survival and for overall survival (p < 0.05). Our findings indicate that over-expression of BMP-2 in malignant fibrous histiocytoma of soft tissue is the most reliable prognostic indicator of the parameters assessed." @default.
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- W1903019968 date "2004-05-01" @default.
- W1903019968 modified "2023-10-14" @default.
- W1903019968 title "The expression and prognostic significance of bone morphogenetic protein-2 in patients with malignant fibrous histiocytoma" @default.
- W1903019968 doi "https://doi.org/10.1302/0301-620x.86b4.14484" @default.
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