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- W1904713133 abstract "In the European Community Respiratory Health Survey, 10933 subjects aged 20-44 years (29 centers, 14 countries) had both a baseline (1991/3) and a follow-up (2000/2) evaluation. The degree of baseline BHR was defined in 8136 (74%) subjects as absent (PD20>1 mg) (n=6852); and low (PD20, mg: (0.5-1]), medium (0.15-0.5] or high (0-0.15], based on PD20 distribution tertiles). Two-level logistic regression models (2nd level: centers) were used to analyze the association between BHR degree and new onset of nasal allergies (allergic rhinitis, AR) and COPD (pre-bronchodilator FEV/FVC 0.35 kU/L to cat, mite, grass or Cladosporium) at baseline. An increased BHR degree was associated with an increased risk of developing COPD, asthma and asthma-like symptoms 9 years later (see table). These preliminary analyses support the interest for BHR degree as a predictor of several adult-onset respiratory diseases." @default.
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- W1904713133 date "2011-09-01" @default.
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- W1904713133 title "Degree of bronchial hyperresponsiveness (BHR) and new onset of respiratory diseases 9 years later" @default.
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