Matches in SemOpenAlex for { <https://semopenalex.org/work/W1905053669> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1905053669 endingPage "58" @default.
- W1905053669 startingPage "48" @default.
- W1905053669 abstract "The Bezold-Jarisch reflex is an eponym for a triad of responses (apnea, bradycardia, and hypotension) following intravenous injection of veratrum alkaloids in experimental animals. The observation was first reported in 1867 by von Bezold and Hirt, and confirmed in 1938-1940 by Jarisch. The triad depends on intact vagi and is mediated through cranial nervous medullary centers controlling respiration, heart rate, and vasomotor tone. The respiratory effects are mediated through pulmonary vagal afferents and the bradycardia and vasodepression through cardiac vagal afferents. The veratrum alkaloids activate all known receptors in the carotid-aortic and cardiopulmonary areas. The cardiopulmonary receptors (baroreceptors, cough receptors, and parenchymal stretch receptors) also respond to other chemical substances: nicotine, capsaicin, venom, antihistaminics, halogenated anesthetics, diguanides, and serotonin (5-hydroxytryptamine). Derivatives of last-mentioned amine activate Type 1, 2, or 3 receptors and have potential therapeutic use. Since several types of cardiopulmonary receptors participate in the Bezold-Jarisch reflex, it has been difficult to develop a blockade to one type of receptor for therapeutic use (cough, bronchospasm, pulmonary hypertension, or coronary vasospasm). Axon reflexes influence pulmonary blood vessels, bronchial blood vessels, and bronchial smooth muscles. These intrapulmonary reflexes need further study as to how they relate to the Bezold-Jarisch reflex in health and disease. The cardiopulmonary and carotid-aortic reflexes can serve as defense mechanisms against chemical hazards that are likely to be inhaled in the workplace and in the environment." @default.
- W1905053669 created "2016-06-24" @default.
- W1905053669 creator A5046549761 @default.
- W1905053669 creator A5081514869 @default.
- W1905053669 date "2001-06-01" @default.
- W1905053669 modified "2023-09-27" @default.
- W1905053669 title "The Bezold-Jarisch reflex. A historical perspective of cardiopulmonary reflexes." @default.
- W1905053669 cites W1559032750 @default.
- W1905053669 cites W1969618052 @default.
- W1905053669 cites W1981131941 @default.
- W1905053669 cites W1986059762 @default.
- W1905053669 cites W1987878858 @default.
- W1905053669 cites W2003639062 @default.
- W1905053669 cites W2025163995 @default.
- W1905053669 cites W2031841598 @default.
- W1905053669 cites W2043399070 @default.
- W1905053669 cites W2047802569 @default.
- W1905053669 cites W2055884839 @default.
- W1905053669 cites W2056536207 @default.
- W1905053669 cites W2075101419 @default.
- W1905053669 cites W2075977613 @default.
- W1905053669 cites W2092541916 @default.
- W1905053669 cites W2128221835 @default.
- W1905053669 cites W2135179417 @default.
- W1905053669 cites W2180890583 @default.
- W1905053669 cites W2268089791 @default.
- W1905053669 cites W2409485668 @default.
- W1905053669 cites W2424190419 @default.
- W1905053669 cites W2469777766 @default.
- W1905053669 cites W3093330030 @default.
- W1905053669 cites W63574133 @default.
- W1905053669 cites W19649661 @default.
- W1905053669 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11458703" @default.
- W1905053669 hasPublicationYear "2001" @default.
- W1905053669 type Work @default.
- W1905053669 sameAs 1905053669 @default.
- W1905053669 citedByCount "52" @default.
- W1905053669 countsByYear W19050536692012 @default.
- W1905053669 countsByYear W19050536692013 @default.
- W1905053669 countsByYear W19050536692014 @default.
- W1905053669 countsByYear W19050536692015 @default.
- W1905053669 countsByYear W19050536692016 @default.
- W1905053669 countsByYear W19050536692017 @default.
- W1905053669 countsByYear W19050536692018 @default.
- W1905053669 countsByYear W19050536692019 @default.
- W1905053669 countsByYear W19050536692021 @default.
- W1905053669 countsByYear W19050536692022 @default.
- W1905053669 countsByYear W19050536692023 @default.
- W1905053669 crossrefType "journal-article" @default.
- W1905053669 hasAuthorship W1905053669A5046549761 @default.
- W1905053669 hasAuthorship W1905053669A5081514869 @default.
- W1905053669 hasConcept C126322002 @default.
- W1905053669 hasConcept C2777495988 @default.
- W1905053669 hasConcept C2777953023 @default.
- W1905053669 hasConcept C42219234 @default.
- W1905053669 hasConcept C71924100 @default.
- W1905053669 hasConcept C83974742 @default.
- W1905053669 hasConcept C84393581 @default.
- W1905053669 hasConceptScore W1905053669C126322002 @default.
- W1905053669 hasConceptScore W1905053669C2777495988 @default.
- W1905053669 hasConceptScore W1905053669C2777953023 @default.
- W1905053669 hasConceptScore W1905053669C42219234 @default.
- W1905053669 hasConceptScore W1905053669C71924100 @default.
- W1905053669 hasConceptScore W1905053669C83974742 @default.
- W1905053669 hasConceptScore W1905053669C84393581 @default.
- W1905053669 hasLocation W19050536691 @default.
- W1905053669 hasOpenAccess W1905053669 @default.
- W1905053669 hasPrimaryLocation W19050536691 @default.
- W1905053669 hasRelatedWork W2019086812 @default.
- W1905053669 hasRelatedWork W2022948112 @default.
- W1905053669 hasRelatedWork W2094292084 @default.
- W1905053669 hasRelatedWork W2176759326 @default.
- W1905053669 hasRelatedWork W2254048216 @default.
- W1905053669 hasRelatedWork W2358087159 @default.
- W1905053669 hasRelatedWork W2501390164 @default.
- W1905053669 hasRelatedWork W2917524362 @default.
- W1905053669 hasRelatedWork W3027280922 @default.
- W1905053669 hasRelatedWork W4210887191 @default.
- W1905053669 hasVolume "940" @default.
- W1905053669 isParatext "false" @default.
- W1905053669 isRetracted "false" @default.
- W1905053669 magId "1905053669" @default.
- W1905053669 workType "article" @default.