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• W1905935802 endingPage "413" @default.
• W1905935802 startingPage "402" @default.
• W1905935802 abstract "Sudden unexpected death in epilepsy (SUDEP) is the most common cause of death in patients with intractable epilepsy. The substantial lifetime risk of SUDEP and the lack of a clear pathophysiological connection between epilepsy itself and sudden death have fuelled increased attention to this phenomenon. Understanding the mechanisms underlying SUDEP is paramount to developing preventative strategies. In this review, we discuss SUDEP population studies, case-control studies, witnessed and monitored cases, as well as human seizure cardiorespiratory findings related to SUDEP, and SUDEP animal models. We integrate these data to suggest the most probable mechanisms underlying SUDEP. Understanding the modifiable risk factors and pathophysiology allows us to discuss potential preventative strategies." @default.
• W1905935802 created "2016-06-24" @default.
• W1905935802 creator A5028152878 @default.
• W1905935802 creator A5033922320 @default.
• W1905935802 creator A5037071752 @default.
• W1905935802 date "2015-06-02" @default.
• W1905935802 modified "2023-10-02" @default.
• W1905935802 title "Sudden unexpected death in epilepsy: basic mechanisms and clinical implications for prevention" @default.
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