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- W1906592865 abstract "The neutrophil-immobilizing factor (NIF) derived from human leukocytes inhibited the random migration and chemotactic response of purified human neutrophils and eosinophils but not of monocytes. Concentrations of NIF sufficient to suppress mobility did not diminish phagocytic capacity or adherence to plastic Petri dishes of human neutrophils; the increased activity of the hexose monophosphate shunt associated with either phagocytosis or direct interaction with chemotactically active concentrations of kallikrein or C5a was also not suppressed. It is postulated that the in vivo role of NIF may relate to its ability to concentrate neutrophils in inflammatory foci without depressing their phagocytic potential or metabolic activation." @default.
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- W1906592865 date "1973-09-01" @default.
- W1906592865 modified "2023-09-29" @default.
- W1906592865 title "A neutrophil immobilizing factor derived from human leukocytes. II. Specificity of action on polymorphonuclear leukocyte mobility." @default.
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