Matches in SemOpenAlex for { <https://semopenalex.org/work/W1907009478> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W1907009478 abstract "Many of the present limitations of peripheral nerve repair might be overcome by performing nerve repairs at the axon level. One approach to nerve repair at this level would be to implant a neuroprosthesis in the form of a microelectronic switchboard which could route the connections of regenerated axons to their correct destinations. This requires a merger of microsurgery and microelectronics. Three steps are needed to achieve this goal. (1) The achievement of in vivo compatibility and electrical contact between axons and a material compatible with microelectronics. (2) The fabrication of a microelectronic neuroprosthesis with electrodes to establish communication with the axon. (3) The development of signal processing hardware and software to control the mapping of the regenerated axons. This report describes preliminary experiments in regenerating peripheral nerve axons through an electronic-grade silicon chip with laser-drilled holes small enough to capture either one or a few axons per hole. We have observed the viability of such nerves in 4 rats for 6 months to 1 year, and in two primates for more than 3 months. As our experiments show, this technique is not yet as effective as suture repair, but the development of a neuroprosthesis that communicates with peripheral nerve axons could have applications including nerve repair, neuroma, and nerve grafts, as well as interfacing the peripheral nervous system to prostheses of other kinds." @default.
- W1907009478 created "2016-06-24" @default.
- W1907009478 creator A5009426049 @default.
- W1907009478 creator A5030008115 @default.
- W1907009478 creator A5030946711 @default.
- W1907009478 date "1990-01-01" @default.
- W1907009478 modified "2023-10-06" @default.
- W1907009478 title "Preliminary experiments in nerve regeneration through laser-drilled holes in silicon chips" @default.
- W1907009478 doi "https://doi.org/10.3233/rnn-1990-2205" @default.
- W1907009478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21551590" @default.
- W1907009478 hasPublicationYear "1990" @default.
- W1907009478 type Work @default.
- W1907009478 sameAs 1907009478 @default.
- W1907009478 citedByCount "8" @default.
- W1907009478 countsByYear W19070094782013 @default.
- W1907009478 countsByYear W19070094782018 @default.
- W1907009478 countsByYear W19070094782020 @default.
- W1907009478 countsByYear W19070094782021 @default.
- W1907009478 crossrefType "journal-article" @default.
- W1907009478 hasAuthorship W1907009478A5009426049 @default.
- W1907009478 hasAuthorship W1907009478A5030008115 @default.
- W1907009478 hasAuthorship W1907009478A5030946711 @default.
- W1907009478 hasConcept C105702510 @default.
- W1907009478 hasConcept C136229726 @default.
- W1907009478 hasConcept C136940099 @default.
- W1907009478 hasConcept C169760540 @default.
- W1907009478 hasConcept C171056886 @default.
- W1907009478 hasConcept C171250308 @default.
- W1907009478 hasConcept C187937830 @default.
- W1907009478 hasConcept C192562407 @default.
- W1907009478 hasConcept C197525751 @default.
- W1907009478 hasConcept C2779530196 @default.
- W1907009478 hasConcept C2779649809 @default.
- W1907009478 hasConcept C3018498973 @default.
- W1907009478 hasConcept C41008148 @default.
- W1907009478 hasConcept C71924100 @default.
- W1907009478 hasConcept C86803240 @default.
- W1907009478 hasConcept C95444343 @default.
- W1907009478 hasConceptScore W1907009478C105702510 @default.
- W1907009478 hasConceptScore W1907009478C136229726 @default.
- W1907009478 hasConceptScore W1907009478C136940099 @default.
- W1907009478 hasConceptScore W1907009478C169760540 @default.
- W1907009478 hasConceptScore W1907009478C171056886 @default.
- W1907009478 hasConceptScore W1907009478C171250308 @default.
- W1907009478 hasConceptScore W1907009478C187937830 @default.
- W1907009478 hasConceptScore W1907009478C192562407 @default.
- W1907009478 hasConceptScore W1907009478C197525751 @default.
- W1907009478 hasConceptScore W1907009478C2779530196 @default.
- W1907009478 hasConceptScore W1907009478C2779649809 @default.
- W1907009478 hasConceptScore W1907009478C3018498973 @default.
- W1907009478 hasConceptScore W1907009478C41008148 @default.
- W1907009478 hasConceptScore W1907009478C71924100 @default.
- W1907009478 hasConceptScore W1907009478C86803240 @default.
- W1907009478 hasConceptScore W1907009478C95444343 @default.
- W1907009478 hasLocation W19070094781 @default.
- W1907009478 hasLocation W19070094782 @default.
- W1907009478 hasOpenAccess W1907009478 @default.
- W1907009478 hasPrimaryLocation W19070094781 @default.
- W1907009478 hasRelatedWork W1535678544 @default.
- W1907009478 hasRelatedWork W1807577481 @default.
- W1907009478 hasRelatedWork W1874125315 @default.
- W1907009478 hasRelatedWork W1974827846 @default.
- W1907009478 hasRelatedWork W1978350486 @default.
- W1907009478 hasRelatedWork W1985803956 @default.
- W1907009478 hasRelatedWork W2010021349 @default.
- W1907009478 hasRelatedWork W2020307886 @default.
- W1907009478 hasRelatedWork W2024789446 @default.
- W1907009478 hasRelatedWork W2026234338 @default.
- W1907009478 hasRelatedWork W2029387532 @default.
- W1907009478 hasRelatedWork W2033812657 @default.
- W1907009478 hasRelatedWork W2051753303 @default.
- W1907009478 hasRelatedWork W2053517954 @default.
- W1907009478 hasRelatedWork W2072571580 @default.
- W1907009478 hasRelatedWork W2102823461 @default.
- W1907009478 hasRelatedWork W2119102687 @default.
- W1907009478 hasRelatedWork W2122927536 @default.
- W1907009478 hasRelatedWork W2124792768 @default.
- W1907009478 hasRelatedWork W2417684263 @default.
- W1907009478 isParatext "false" @default.
- W1907009478 isRetracted "false" @default.
- W1907009478 magId "1907009478" @default.
- W1907009478 workType "article" @default.