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- W1907169523 endingPage "1107" @default.
- W1907169523 startingPage "1096" @default.
- W1907169523 abstract "Eosinophilic oesophagitis (EO) is an increasingly recognised chronic, relapsing inflammatory condition of the oesophagus. There has been a mini-epidemic of EO in the last decade. The incidence of this condition is higher in children and is commoner in males. There is either a family or personal history of atopic conditions present in a significant number of patients and can also be familial in up to 10%. The classical symptom in an adult is chronic, intermittent solid-food dysphagia and food impaction, often necessitating emergency endoscopic removal. Despite the history of dysphagia for a number of years, patients remain well with no weight loss, which can mislead clinicians to diagnose a functional problem with a resulting delay in the diagnosis. There are various endoscopic features of EO; commonly multiple rings and linear furrows, though these can be subtle and the mucosa may be macroscopically normal. The hallmark of this condition is the histological presence of > or =15 eosinophils/high power field (HPF) in the oesophageal mucosa. Therapeutic options include avoidance of dietary allergens, topical or systemic steroids, Montelukast, Mepolizumab (anti-IL-5 antibody) and endoscopic dilation of strictures unresponsive to medical therapy." @default.
- W1907169523 created "2016-06-24" @default.
- W1907169523 creator A5056341880 @default.
- W1907169523 creator A5060457326 @default.
- W1907169523 date "2008-06-04" @default.
- W1907169523 modified "2023-09-24" @default.
- W1907169523 title "Eosinophilic oesophagitis: a common cause of dysphagia in young adults?" @default.
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- W1907169523 doi "https://doi.org/10.1111/j.1742-1241.2008.01782.x" @default.
- W1907169523 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18564273" @default.
- W1907169523 hasPublicationYear "2008" @default.
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