Matches in SemOpenAlex for { <https://semopenalex.org/work/W1907505870> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W1907505870 endingPage "1451" @default.
- W1907505870 startingPage "1447" @default.
- W1907505870 abstract "Methotrexate (MTX) is a well-known systemic drug for moderate to severe chronic plaque psoriasis. Recently, mycophenolate mofetil (MMF) has been recommended for psoriasis.To compare the efficacy and safety of MMF vs. MTX for the treatment of chronic plaque psoriasis.Thirty-eight consecutive patients with Psoriasis Area and Severity Index (PASI)>10 were randomly assigned for 12 weeks of treatment with either MTX (18 patients; initial dose, 7.5 mg/week) or MMF (20 patients; dose; 2 g/day) and were followed for 12 weeks after discontinuing the treatment. The differences between the two groups were analysed at the end of treatment and follow-up comparing with baseline values.After 12 weeks of treatment, the mean ± SD score for the PASI decreased from 16.46 ± 5.29 at baseline to 3.17 ± 2.35 among 15 patients treated with MTX, whereas the score decreased from 17.43 ± 7.42 to 3.97 ± 5.95 among 17 patients treated with MMF (P>0.05). Twelve weeks after discontinuing the treatment, the scores were 4.77 ± 3.52 and 5.94 ± 4.27, respectively (P>0.05). PASI -75 were achieved in 58.8% of patients in MMF group and 73.3% in MTX group (P > 0.05). Three months after discontinuing the treatment, PASI-75 remained in 33.3% of patients in MMF and 53.3% of MTX group (P > 0.05). Both drugs were well tolerated and side-effects were minor and transient.No significant differences in efficacy were found between MTX and MMF groups. MMF may represent a good alternative for the treatment of psoriasis in patients who are unable to take MTX or other available drugs due to contraindication or toxicity." @default.
- W1907505870 created "2016-06-24" @default.
- W1907505870 creator A5013838372 @default.
- W1907505870 creator A5045559434 @default.
- W1907505870 creator A5047286483 @default.
- W1907505870 creator A5052580396 @default.
- W1907505870 date "2010-11-09" @default.
- W1907505870 modified "2023-10-14" @default.
- W1907505870 title "Efficacy and safety of mycophenolate mofetil vs. methotrexate for the treatment of chronic plaque psoriasis" @default.
- W1907505870 cites W1486769243 @default.
- W1907505870 cites W1976717494 @default.
- W1907505870 cites W1993359206 @default.
- W1907505870 cites W1996773947 @default.
- W1907505870 cites W2005375392 @default.
- W1907505870 cites W2024445459 @default.
- W1907505870 cites W2027703023 @default.
- W1907505870 cites W2067327580 @default.
- W1907505870 cites W2085863730 @default.
- W1907505870 cites W2103064056 @default.
- W1907505870 cites W2121234952 @default.
- W1907505870 cites W2121588356 @default.
- W1907505870 cites W2127114114 @default.
- W1907505870 cites W2163232748 @default.
- W1907505870 cites W3021452643 @default.
- W1907505870 cites W4233727453 @default.
- W1907505870 cites W4241553124 @default.
- W1907505870 doi "https://doi.org/10.1111/j.1468-3083.2010.03667.x" @default.
- W1907505870 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20384673" @default.
- W1907505870 hasPublicationYear "2010" @default.
- W1907505870 type Work @default.
- W1907505870 sameAs 1907505870 @default.
- W1907505870 citedByCount "49" @default.
- W1907505870 countsByYear W19075058702012 @default.
- W1907505870 countsByYear W19075058702013 @default.
- W1907505870 countsByYear W19075058702014 @default.
- W1907505870 countsByYear W19075058702015 @default.
- W1907505870 countsByYear W19075058702016 @default.
- W1907505870 countsByYear W19075058702017 @default.
- W1907505870 countsByYear W19075058702018 @default.
- W1907505870 countsByYear W19075058702019 @default.
- W1907505870 countsByYear W19075058702020 @default.
- W1907505870 countsByYear W19075058702021 @default.
- W1907505870 countsByYear W19075058702022 @default.
- W1907505870 countsByYear W19075058702023 @default.
- W1907505870 crossrefType "journal-article" @default.
- W1907505870 hasAuthorship W1907505870A5013838372 @default.
- W1907505870 hasAuthorship W1907505870A5045559434 @default.
- W1907505870 hasAuthorship W1907505870A5047286483 @default.
- W1907505870 hasAuthorship W1907505870A5052580396 @default.
- W1907505870 hasConcept C126322002 @default.
- W1907505870 hasConcept C141071460 @default.
- W1907505870 hasConcept C16005928 @default.
- W1907505870 hasConcept C197934379 @default.
- W1907505870 hasConcept C2777011040 @default.
- W1907505870 hasConcept C2780564577 @default.
- W1907505870 hasConcept C2781059491 @default.
- W1907505870 hasConcept C2909935303 @default.
- W1907505870 hasConcept C2911091166 @default.
- W1907505870 hasConcept C3020604521 @default.
- W1907505870 hasConcept C71924100 @default.
- W1907505870 hasConcept C90924648 @default.
- W1907505870 hasConceptScore W1907505870C126322002 @default.
- W1907505870 hasConceptScore W1907505870C141071460 @default.
- W1907505870 hasConceptScore W1907505870C16005928 @default.
- W1907505870 hasConceptScore W1907505870C197934379 @default.
- W1907505870 hasConceptScore W1907505870C2777011040 @default.
- W1907505870 hasConceptScore W1907505870C2780564577 @default.
- W1907505870 hasConceptScore W1907505870C2781059491 @default.
- W1907505870 hasConceptScore W1907505870C2909935303 @default.
- W1907505870 hasConceptScore W1907505870C2911091166 @default.
- W1907505870 hasConceptScore W1907505870C3020604521 @default.
- W1907505870 hasConceptScore W1907505870C71924100 @default.
- W1907505870 hasConceptScore W1907505870C90924648 @default.
- W1907505870 hasIssue "12" @default.
- W1907505870 hasLocation W19075058701 @default.
- W1907505870 hasLocation W19075058702 @default.
- W1907505870 hasOpenAccess W1907505870 @default.
- W1907505870 hasPrimaryLocation W19075058701 @default.
- W1907505870 hasRelatedWork W2165317030 @default.
- W1907505870 hasRelatedWork W2520935772 @default.
- W1907505870 hasRelatedWork W2894240066 @default.
- W1907505870 hasRelatedWork W2898213950 @default.
- W1907505870 hasRelatedWork W2963043097 @default.
- W1907505870 hasRelatedWork W3108657795 @default.
- W1907505870 hasRelatedWork W3159096017 @default.
- W1907505870 hasRelatedWork W4213143336 @default.
- W1907505870 hasRelatedWork W4294670165 @default.
- W1907505870 hasRelatedWork W4311073028 @default.
- W1907505870 hasVolume "24" @default.
- W1907505870 isParatext "false" @default.
- W1907505870 isRetracted "false" @default.
- W1907505870 magId "1907505870" @default.
- W1907505870 workType "article" @default.