Matches in SemOpenAlex for { <https://semopenalex.org/work/W1907672011> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W1907672011 endingPage "1238" @default.
- W1907672011 startingPage "1231" @default.
- W1907672011 abstract "Thirty-five consecutive patients with resectable adenocarcinoma of the esophagus or gastroesophageal junction were treated with two preoperative and three or four postoperative chemotherapy courses consisting of etoposide, fluorouracil, and cisplatin (EFP) to evaluate the rate of curative resection, clinical and pathologic response, toxic effects, and survival. One hundred thirty-seven courses with a median number of five courses (range, one to six) were administered. Preoperative EFP resulted in 17 (49%) major responses, including six patients who did not have carcinoma cells in the repeat endoscopic biopsy specimens and cytologic brushings. Among 32 patients who had surgery, 25 (78%) had curative resection, one patient had a complete pathologic response, and one had microscopic carcinoma in the resected specimen. Six patients had microscopic carcinoma at the resection margins and received postoperative radiotherapy. At a median follow-up of 20 months, the projected survival of 35 patients is 23 months (range, 6 to 33+). Fifteen patients died of their carcinomas, and 15 patients were alive (median follow-up, 20+ months; range, 15+ to 33+ months) with no evidence of relapse. There were no deaths related to chemotherapy, surgery, or radiotherapy. EFP-induced toxic reactions were moderate. Our data suggest that multiple courses of EFP are feasible. Future strategies for this disease should consider prolonged chemotherapy with regimens that result frequently in pathologic complete responses." @default.
- W1907672011 created "2016-06-24" @default.
- W1907672011 creator A5017764456 @default.
- W1907672011 creator A5018278944 @default.
- W1907672011 creator A5021101281 @default.
- W1907672011 creator A5025664431 @default.
- W1907672011 creator A5027152610 @default.
- W1907672011 creator A5044064524 @default.
- W1907672011 creator A5083468519 @default.
- W1907672011 creator A5085652701 @default.
- W1907672011 creator A5087376683 @default.
- W1907672011 creator A5087548710 @default.
- W1907672011 date "1990-07-01" @default.
- W1907672011 modified "2023-09-27" @default.
- W1907672011 title "Evaluation of pre- and postoperative chemotherapy for resectable adenocarcinoma of the esophagus or gastroesophageal junction." @default.
- W1907672011 doi "https://doi.org/10.1200/jco.1990.8.7.1231" @default.
- W1907672011 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2358838" @default.
- W1907672011 hasPublicationYear "1990" @default.
- W1907672011 type Work @default.
- W1907672011 sameAs 1907672011 @default.
- W1907672011 citedByCount "98" @default.
- W1907672011 countsByYear W19076720112012 @default.
- W1907672011 countsByYear W19076720112013 @default.
- W1907672011 countsByYear W19076720112014 @default.
- W1907672011 countsByYear W19076720112015 @default.
- W1907672011 countsByYear W19076720112021 @default.
- W1907672011 countsByYear W19076720112022 @default.
- W1907672011 crossrefType "journal-article" @default.
- W1907672011 hasAuthorship W1907672011A5017764456 @default.
- W1907672011 hasAuthorship W1907672011A5018278944 @default.
- W1907672011 hasAuthorship W1907672011A5021101281 @default.
- W1907672011 hasAuthorship W1907672011A5025664431 @default.
- W1907672011 hasAuthorship W1907672011A5027152610 @default.
- W1907672011 hasAuthorship W1907672011A5044064524 @default.
- W1907672011 hasAuthorship W1907672011A5083468519 @default.
- W1907672011 hasAuthorship W1907672011A5085652701 @default.
- W1907672011 hasAuthorship W1907672011A5087376683 @default.
- W1907672011 hasAuthorship W1907672011A5087548710 @default.
- W1907672011 hasConcept C121608353 @default.
- W1907672011 hasConcept C126322002 @default.
- W1907672011 hasConcept C126838900 @default.
- W1907672011 hasConcept C141071460 @default.
- W1907672011 hasConcept C2775934546 @default.
- W1907672011 hasConcept C2776694085 @default.
- W1907672011 hasConcept C2777546739 @default.
- W1907672011 hasConcept C2777819096 @default.
- W1907672011 hasConcept C2778119113 @default.
- W1907672011 hasConcept C2781182431 @default.
- W1907672011 hasConcept C509974204 @default.
- W1907672011 hasConcept C71924100 @default.
- W1907672011 hasConceptScore W1907672011C121608353 @default.
- W1907672011 hasConceptScore W1907672011C126322002 @default.
- W1907672011 hasConceptScore W1907672011C126838900 @default.
- W1907672011 hasConceptScore W1907672011C141071460 @default.
- W1907672011 hasConceptScore W1907672011C2775934546 @default.
- W1907672011 hasConceptScore W1907672011C2776694085 @default.
- W1907672011 hasConceptScore W1907672011C2777546739 @default.
- W1907672011 hasConceptScore W1907672011C2777819096 @default.
- W1907672011 hasConceptScore W1907672011C2778119113 @default.
- W1907672011 hasConceptScore W1907672011C2781182431 @default.
- W1907672011 hasConceptScore W1907672011C509974204 @default.
- W1907672011 hasConceptScore W1907672011C71924100 @default.
- W1907672011 hasIssue "7" @default.
- W1907672011 hasLocation W19076720111 @default.
- W1907672011 hasLocation W19076720112 @default.
- W1907672011 hasOpenAccess W1907672011 @default.
- W1907672011 hasPrimaryLocation W19076720111 @default.
- W1907672011 hasRelatedWork W1972181016 @default.
- W1907672011 hasRelatedWork W1987769508 @default.
- W1907672011 hasRelatedWork W2014435840 @default.
- W1907672011 hasRelatedWork W2082691227 @default.
- W1907672011 hasRelatedWork W2348495938 @default.
- W1907672011 hasRelatedWork W2364854402 @default.
- W1907672011 hasRelatedWork W2389384568 @default.
- W1907672011 hasRelatedWork W2409999721 @default.
- W1907672011 hasRelatedWork W2411669476 @default.
- W1907672011 hasRelatedWork W2432975745 @default.
- W1907672011 hasVolume "8" @default.
- W1907672011 isParatext "false" @default.
- W1907672011 isRetracted "false" @default.
- W1907672011 magId "1907672011" @default.
- W1907672011 workType "article" @default.