FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1907795058> ?p ?o ?g. }

• W1907795058 endingPage "409" @default.
• W1907795058 startingPage "409" @default.
• W1907795058 abstract "To review the pharmacodynamics, pharmacokinetics, toxicities, and relative clinical activities of cisplatin and carboplatin. Through a search of the MEDLINE database, we identified phase III clinical trials and pharmacologic studies comparing cisplatin and carboplatin published in the English language medical literature from January 1966 to December 1997.Prospective randomized trials comparing cisplatin to carboplatin were identified for ovarian (n = 12), germ cell (n = 4), non-small-cell lung (n = 1), small-cell lung (n = 3), and head and neck (n = 4) cancers. Carboplatin and cisplatin were equally effective in suboptimally debulked ovarian cancer and extensive-stage small-cell lung cancer. One study each showed a trend toward better survival in favor of cisplatin for patients with optimally debulked ovarian and limited-stage small-cell lung cancers. These results were, however, based on subset analyses. In germ cell tumors, carboplatin was inferior because of lower relapse-free survival rates. Cisplatin produced superior response rates and survival in head and neck cancers. There are no published randomized phase III studies of bladder, cervical, endometrial, and esophageal cancers.Carboplatin does not possess equivalent activity to cisplatin in all platinum-sensitive tumors. Carboplatin can replace cisplatin in chemotherapy regimens for suboptimally debulked ovarian cancer. Two ongoing studies will address the same question in optimally debulked disease. Carboplatin can also be substituted for cisplatin in the treatment of non-small-cell and extensive-stage small-cell lung cancers. Its role in limited-stage small-cell lung cancer needs to be investigated further. Carboplatin is inferior to cisplatin in germ cell, head and neck, and esophageal cancers. Randomized studies are needed to determine whether carboplatin has equivalent efficacy to cisplatin in bladder, cervical, and endometrial cancers." @default.
• W1907795058 created "2016-06-24" @default.
• W1907795058 creator A5029802364 @default.
• W1907795058 creator A5041114807 @default.
• W1907795058 date "1999-01-01" @default.
• W1907795058 modified "2023-10-16" @default.
• W1907795058 title "Review of the Comparative Pharmacology and Clinical Activity of Cisplatin and Carboplatin" @default.
• W1907795058 cites W1480834102 @default.
• W1907795058 cites W1504784308 @default.
• W1907795058 cites W1506983576 @default.
• W1907795058 cites W1723772693 @default.
• W1907795058 cites W1790560776 @default.
• W1907795058 cites W1832113570 @default.
• W1907795058 cites W1841674624 @default.
• W1907795058 cites W1849826284 @default.
• W1907795058 cites W1851054576 @default.
• W1907795058 cites W1893740135 @default.
• W1907795058 cites W1903188031 @default.
• W1907795058 cites W1903927332 @default.
• W1907795058 cites W1904556507 @default.
• W1907795058 cites W1932754573 @default.
• W1907795058 cites W1936253731 @default.
• W1907795058 cites W1975044674 @default.
• W1907795058 cites W1975316159 @default.
• W1907795058 cites W1976533707 @default.
• W1907795058 cites W1980411311 @default.
• W1907795058 cites W1981534925 @default.
• W1907795058 cites W1983426353 @default.
• W1907795058 cites W1990733040 @default.
• W1907795058 cites W1991191453 @default.
• W1907795058 cites W2000886567 @default.
• W1907795058 cites W2001436364 @default.
• W1907795058 cites W2002314919 @default.
• W1907795058 cites W2002671562 @default.
• W1907795058 cites W2003014855 @default.
• W1907795058 cites W2006974151 @default.
• W1907795058 cites W2008281779 @default.
• W1907795058 cites W2011743008 @default.
• W1907795058 cites W2012733679 @default.
• W1907795058 cites W2026097725 @default.
• W1907795058 cites W2027938725 @default.
• W1907795058 cites W2032528970 @default.
• W1907795058 cites W2035186429 @default.
• W1907795058 cites W2037199558 @default.
• W1907795058 cites W2039331746 @default.
• W1907795058 cites W2041219929 @default.
• W1907795058 cites W2042044981 @default.
• W1907795058 cites W2044390866 @default.
• W1907795058 cites W2053495438 @default.
• W1907795058 cites W2058734928 @default.
• W1907795058 cites W2064044157 @default.
• W1907795058 cites W2064411691 @default.
• W1907795058 cites W2069041300 @default.
• W1907795058 cites W2073037820 @default.
• W1907795058 cites W2074564480 @default.
• W1907795058 cites W2076746136 @default.
• W1907795058 cites W2078144803 @default.
• W1907795058 cites W2088865525 @default.
• W1907795058 cites W2116996913 @default.
• W1907795058 cites W2129793485 @default.
• W1907795058 cites W2135578643 @default.
• W1907795058 cites W2141783551 @default.
• W1907795058 cites W2145351799 @default.
• W1907795058 cites W2152821057 @default.
• W1907795058 cites W2155202687 @default.
• W1907795058 cites W2164832682 @default.
• W1907795058 cites W2165673827 @default.
• W1907795058 cites W2168284025 @default.
• W1907795058 cites W2180897046 @default.
• W1907795058 cites W2252554630 @default.
• W1907795058 cites W2331986837 @default.
• W1907795058 cites W2475514305 @default.
• W1907795058 cites W4210704032 @default.
• W1907795058 cites W4239714259 @default.
• W1907795058 cites W4241269322 @default.
• W1907795058 cites W4244568420 @default.
• W1907795058 cites W44254208 @default.
• W1907795058 doi "https://doi.org/10.1200/jco.1999.17.1.409" @default.
• W1907795058 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10458260" @default.
• W1907795058 hasPublicationYear "1999" @default.
• W1907795058 type Work @default.
• W1907795058 sameAs 1907795058 @default.
• W1907795058 citedByCount "606" @default.
• W1907795058 countsByYear W19077950582012 @default.
• W1907795058 countsByYear W19077950582013 @default.
• W1907795058 countsByYear W19077950582014 @default.
• W1907795058 countsByYear W19077950582015 @default.
• W1907795058 countsByYear W19077950582016 @default.
• W1907795058 countsByYear W19077950582017 @default.
• W1907795058 countsByYear W19077950582018 @default.
• W1907795058 countsByYear W19077950582019 @default.
• W1907795058 countsByYear W19077950582020 @default.
• W1907795058 countsByYear W19077950582021 @default.
• W1907795058 countsByYear W19077950582022 @default.
• W1907795058 countsByYear W19077950582023 @default.
• W1907795058 crossrefType "journal-article" @default.
• W1907795058 hasAuthorship W1907795058A5029802364 @default.
• W1907795058 hasAuthorship W1907795058A5041114807 @default.

• next