Matches in SemOpenAlex for { <https://semopenalex.org/work/W1907897284> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W1907897284 endingPage "340" @default.
- W1907897284 startingPage "335" @default.
- W1907897284 abstract "Background. Hyperacute graft-versus-host disease (GVHD) is defined as GVHD occurring within 14 days after haematopoietic stem-cell transplantation (HSCT). Aim. To evaluate the usefulness of skin biopsy in assessing hyperacute GVHD. Methods. We examined 19 cases of hyperacute GVHD from a total of 134 consecutive HSCT cases at Shinshu University Hospital between 1999 and 2008. Results. Exanthemas were seen in all patients, which were mainly disseminated maculopapular erythemas, commonly present in acute GVHD as well. Most patients presented with a high fever, and a few had mild hepatic dysfunction and/or diarrhoea. The clinical grade of GVHD was 1–2 in all patients; there were no cases of clinical grades 3–4. The histological findings of skin biopsy were divided into three groups: (i) eight had grade 2 changes, characterized by diffuse vacuolization of basal cells, with dyskeratotic bodies; (ii) five had grade 1 changes, characterized by vacuolization of epidermal basal cells (all these cases were diagnosed as acute GVHD with grade 2 histological changes at subsequent biopsy); (iii) and six had no significant changes (these cases were also diagnosed as acute GVHD with grade 2 (four cases) or grade 1 (one case) histological changes on the second biopsy). Many of the patients developed acute and later chronic GVHD. Conclusion. Skin biopsy should be considered when eruption develops after HSCT even before engraftment, especially when other organ involvement is minimal. If the first skin biopsy is inconclusive, follow-up biopsy within a short time is helpful in the diagnosis of hyperacute GVHD." @default.
- W1907897284 created "2016-06-24" @default.
- W1907897284 creator A5015716732 @default.
- W1907897284 creator A5034709519 @default.
- W1907897284 creator A5079616282 @default.
- W1907897284 creator A5080929289 @default.
- W1907897284 creator A5083658207 @default.
- W1907897284 date "2012-01-25" @default.
- W1907897284 modified "2023-09-24" @default.
- W1907897284 title "Hyperacute graft-versus-host disease: histological assessment of skin biopsy specimens from 19 cases" @default.
- W1907897284 cites W1963674865 @default.
- W1907897284 cites W1981150757 @default.
- W1907897284 cites W2023971040 @default.
- W1907897284 cites W2036275987 @default.
- W1907897284 cites W2076610050 @default.
- W1907897284 cites W2126094209 @default.
- W1907897284 cites W2321053053 @default.
- W1907897284 doi "https://doi.org/10.1111/j.1365-2230.2011.04261.x" @default.
- W1907897284 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22276575" @default.
- W1907897284 hasPublicationYear "2012" @default.
- W1907897284 type Work @default.
- W1907897284 sameAs 1907897284 @default.
- W1907897284 citedByCount "5" @default.
- W1907897284 countsByYear W19078972842013 @default.
- W1907897284 countsByYear W19078972842016 @default.
- W1907897284 countsByYear W19078972842018 @default.
- W1907897284 countsByYear W19078972842020 @default.
- W1907897284 countsByYear W19078972842023 @default.
- W1907897284 crossrefType "journal-article" @default.
- W1907897284 hasAuthorship W1907897284A5015716732 @default.
- W1907897284 hasAuthorship W1907897284A5034709519 @default.
- W1907897284 hasAuthorship W1907897284A5079616282 @default.
- W1907897284 hasAuthorship W1907897284A5080929289 @default.
- W1907897284 hasAuthorship W1907897284A5083658207 @default.
- W1907897284 hasConcept C126322002 @default.
- W1907897284 hasConcept C142724271 @default.
- W1907897284 hasConcept C2775934546 @default.
- W1907897284 hasConcept C2778614373 @default.
- W1907897284 hasConcept C2779134260 @default.
- W1907897284 hasConcept C2779972918 @default.
- W1907897284 hasConcept C2780439664 @default.
- W1907897284 hasConcept C2911091166 @default.
- W1907897284 hasConcept C71924100 @default.
- W1907897284 hasConceptScore W1907897284C126322002 @default.
- W1907897284 hasConceptScore W1907897284C142724271 @default.
- W1907897284 hasConceptScore W1907897284C2775934546 @default.
- W1907897284 hasConceptScore W1907897284C2778614373 @default.
- W1907897284 hasConceptScore W1907897284C2779134260 @default.
- W1907897284 hasConceptScore W1907897284C2779972918 @default.
- W1907897284 hasConceptScore W1907897284C2780439664 @default.
- W1907897284 hasConceptScore W1907897284C2911091166 @default.
- W1907897284 hasConceptScore W1907897284C71924100 @default.
- W1907897284 hasIssue "4" @default.
- W1907897284 hasLocation W19078972841 @default.
- W1907897284 hasLocation W19078972842 @default.
- W1907897284 hasOpenAccess W1907897284 @default.
- W1907897284 hasPrimaryLocation W19078972841 @default.
- W1907897284 hasRelatedWork W1907897284 @default.
- W1907897284 hasRelatedWork W2043595386 @default.
- W1907897284 hasRelatedWork W2047832177 @default.
- W1907897284 hasRelatedWork W2086856281 @default.
- W1907897284 hasRelatedWork W2172273597 @default.
- W1907897284 hasRelatedWork W2328560099 @default.
- W1907897284 hasRelatedWork W2942195277 @default.
- W1907897284 hasRelatedWork W2991297133 @default.
- W1907897284 hasRelatedWork W4200066940 @default.
- W1907897284 hasRelatedWork W52325492 @default.
- W1907897284 hasVolume "37" @default.
- W1907897284 isParatext "false" @default.
- W1907897284 isRetracted "false" @default.
- W1907897284 magId "1907897284" @default.
- W1907897284 workType "article" @default.