FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1908908902> ?p ?o ?g. }

• W1908908902 endingPage "16" @default.
• W1908908902 startingPage "1" @default.
• W1908908902 abstract "For the treatment of rabbit dysentery and bacterial enteritis, veterinary practitioners often adopt veterinary medicinal products authorised for other food-producing species, but in some cases non-authorised drugs frequently used in the past, such as carbadox and olaquindox, might be illegally adopted. To verify the carbadox and olaquindox distribution and persistence in rabbit tissues, two independent in vivo studies were carried out. In the first study, 24 healthy rabbits received water medicated with carbadox at 100 mg l−1 over a period 28 days, whereas in the second one, 24 healthy rabbits were administered water containing olaquindox at 100 mg l−1. In each study rabbits were randomly assigned to four groups to be sacrificed respectively at 0, 5, 10 and 20 days from treatment withdrawal, for depletion studies. A control group of six animals was adopted for control and as a reservoir of blank tissues. Muscle and liver samples collected from each treated animal were stored at −20°C pending the analysis. Sensitive and robust liquid chromatography-tandem mass spectrometry analytical methods were set up for the parent compounds and their main metabolites quinoxaline-2-carboxylic acid, desoxycarbadox and 3-methylquinoxaline-2-carboxylic acid to verify their residual. Data collected demonstrate that the combination of liver as target matrix, quinoxaline-2-carboxylic acid and 3-methylquinoxaline-2-carboxylic acid as marker residue and enzymatic digestion is strategic to evidence carbadox and/or olaquindox illegal treatments in rabbits, even 20 days after treatment withdrawal at concentration levels higher than 0.5 µg kg−1. This findings suggests that liver should be proposed as target matrix for official control in national monitoring plan." @default.
• W1908908902 created "2016-06-24" @default.
• W1908908902 creator A5013135249 @default.
• W1908908902 creator A5041482979 @default.
• W1908908902 creator A5050585117 @default.
• W1908908902 creator A5053852536 @default.
• W1908908902 creator A5064497009 @default.
• W1908908902 creator A5069319679 @default.
• W1908908902 date "2015-10-21" @default.
• W1908908902 modified "2023-10-17" @default.
• W1908908902 title "In vivostudies to highlight possible illegal treatments of rabbits with carbadox and olaquindox" @default.
• W1908908902 cites W1499882409 @default.
• W1908908902 cites W1969120150 @default.
• W1908908902 cites W1969766550 @default.
• W1908908902 cites W1973465602 @default.
• W1908908902 cites W1978348498 @default.
• W1908908902 cites W1979553709 @default.
• W1908908902 cites W1979986784 @default.
• W1908908902 cites W1984743848 @default.
• W1908908902 cites W1990075704 @default.
• W1908908902 cites W1993967506 @default.
• W1908908902 cites W2003611873 @default.
• W1908908902 cites W2006516472 @default.
• W1908908902 cites W2018680102 @default.
• W1908908902 cites W2019892872 @default.
• W1908908902 cites W2022062901 @default.
• W1908908902 cites W2023228407 @default.
• W1908908902 cites W2025836549 @default.
• W1908908902 cites W2038684314 @default.
• W1908908902 cites W2057330420 @default.
• W1908908902 cites W2063073476 @default.
• W1908908902 cites W2065267562 @default.
• W1908908902 cites W2075375774 @default.
• W1908908902 cites W2078851558 @default.
• W1908908902 cites W2083413888 @default.
• W1908908902 cites W2088678174 @default.
• W1908908902 cites W2093898951 @default.
• W1908908902 cites W2095112872 @default.
• W1908908902 cites W2105944512 @default.
• W1908908902 cites W2143402058 @default.
• W1908908902 cites W2233071514 @default.
• W1908908902 cites W2285071386 @default.
• W1908908902 cites W337581366 @default.
• W1908908902 doi "https://doi.org/10.1080/19440049.2015.1086822" @default.
• W1908908902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26400201" @default.
• W1908908902 hasPublicationYear "2015" @default.
• W1908908902 type Work @default.
• W1908908902 sameAs 1908908902 @default.
• W1908908902 citedByCount "1" @default.
• W1908908902 countsByYear W19089089022019 @default.
• W1908908902 crossrefType "journal-article" @default.
• W1908908902 hasAuthorship W1908908902A5013135249 @default.
• W1908908902 hasAuthorship W1908908902A5041482979 @default.
• W1908908902 hasAuthorship W1908908902A5050585117 @default.
• W1908908902 hasAuthorship W1908908902A5053852536 @default.
• W1908908902 hasAuthorship W1908908902A5064497009 @default.
• W1908908902 hasAuthorship W1908908902A5069319679 @default.
• W1908908902 hasConcept C178790620 @default.
• W1908908902 hasConcept C185592680 @default.
• W1908908902 hasConcept C2779074116 @default.
• W1908908902 hasConcept C2780362310 @default.
• W1908908902 hasConcept C43617362 @default.
• W1908908902 hasConcept C55493867 @default.
• W1908908902 hasConcept C71924100 @default.
• W1908908902 hasConcept C98274493 @default.
• W1908908902 hasConceptScore W1908908902C178790620 @default.
• W1908908902 hasConceptScore W1908908902C185592680 @default.
• W1908908902 hasConceptScore W1908908902C2779074116 @default.
• W1908908902 hasConceptScore W1908908902C2780362310 @default.
• W1908908902 hasConceptScore W1908908902C43617362 @default.
• W1908908902 hasConceptScore W1908908902C55493867 @default.
• W1908908902 hasConceptScore W1908908902C71924100 @default.
• W1908908902 hasConceptScore W1908908902C98274493 @default.
• W1908908902 hasFunder F4320321781 @default.
• W1908908902 hasLocation W19089089021 @default.
• W1908908902 hasLocation W19089089022 @default.
• W1908908902 hasOpenAccess W1908908902 @default.
• W1908908902 hasPrimaryLocation W19089089021 @default.
• W1908908902 hasRelatedWork W2029160909 @default.
• W1908908902 hasRelatedWork W2066401230 @default.
• W1908908902 hasRelatedWork W2120260316 @default.
• W1908908902 hasRelatedWork W2328710452 @default.
• W1908908902 hasRelatedWork W2343822698 @default.
• W1908908902 hasRelatedWork W2508283963 @default.
• W1908908902 hasRelatedWork W2949327821 @default.
• W1908908902 hasRelatedWork W2949336099 @default.
• W1908908902 hasRelatedWork W2951040459 @default.
• W1908908902 hasRelatedWork W2985275126 @default.
• W1908908902 isParatext "false" @default.
• W1908908902 isRetracted "false" @default.
• W1908908902 magId "1908908902" @default.
• W1908908902 workType "article" @default.