FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1909349784> ?p ?o ?g. }

• W1909349784 endingPage "O57" @default.
• W1909349784 startingPage "O50" @default.
• W1909349784 abstract "Invasive candidiasis is a life-threatening infection in patients with haematological malignancies. The objective of our study was to determine the incidence, microbiological characteristics and clinical outcome of candidaemia among hospitalized adult patients with haematological malignancies. This is a population-based, prospective, multicentre study of patients ≥18 years admitted to haematology and/or haematopoietic stem cell transplantation units of nine tertiary care Greek hospitals from January 2009 through to February 2012. Within this cohort, we conducted a nested case-control study to determine the risk factors for candidaemia. Stepwise logistic regression was used to identify independent predictors of 28-day mortality. Candidaemia was detected in 40 of 27 864 patients with haematological malignancies vs. 967 of 1 158 018 non-haematology patients for an incidence of 1.4 cases/1000 admissions vs. 0.83/1000 respectively (p <0.001). Candidaemia was caused predominantly (35/40, 87.5%) by non-Candida albicans species, particularly Candida parapsilosis (20/40, 50%). In vitro resistance to at least one antifungal agent was observed in 27% of Candida isolates. Twenty-one patients (53%) developed breakthrough candidaemia while receiving antifungal agents. Central venous catheters, hypogammaglobulinaemia and a high APACHE II score were independent risk factors for the development of candidaemia. Crude mortality at day 28 was greater in those with candidaemia than in control cases (18/40 (45%) vs. 9/80 (11%); p <0.0001). In conclusion, despite antifungal prophylaxis, candidaemia is a relatively frequent infection associated with high mortality caused by non-C. albicans spp., especially C. parapsilosis. Central venous catheters and hypogammaglobulinaemia are independent risk factors for candidaemia that provide potential targets for improving the outcome." @default.
• W1909349784 created "2016-06-24" @default.
• W1909349784 creator A5006871789 @default.
• W1909349784 creator A5019102908 @default.
• W1909349784 creator A5037161493 @default.
• W1909349784 creator A5038285556 @default.
• W1909349784 creator A5040387230 @default.
• W1909349784 creator A5043593935 @default.
• W1909349784 creator A5045824682 @default.
• W1909349784 creator A5048001001 @default.
• W1909349784 creator A5050806596 @default.
• W1909349784 creator A5051047557 @default.
• W1909349784 creator A5054607147 @default.
• W1909349784 creator A5062566703 @default.
• W1909349784 creator A5065291460 @default.
• W1909349784 creator A5069171231 @default.
• W1909349784 creator A5070060458 @default.
• W1909349784 creator A5071800632 @default.
• W1909349784 creator A5078995254 @default.
• W1909349784 creator A5084278425 @default.
• W1909349784 creator A5085753272 @default.
• W1909349784 creator A5085951006 @default.
• W1909349784 creator A5086754307 @default.
• W1909349784 creator A5089813116 @default.
• W1909349784 creator A5090123852 @default.
• W1909349784 date "2014-01-01" @default.
• W1909349784 modified "2023-10-10" @default.
• W1909349784 title "A prospective, cohort, multicentre study of candidaemia in hospitalized adult patients with haematological malignancies" @default.
• W1909349784 cites W1653248413 @default.
• W1909349784 cites W1964297378 @default.
• W1909349784 cites W1974342169 @default.
• W1909349784 cites W1976941151 @default.
• W1909349784 cites W1980859250 @default.
• W1909349784 cites W1981025594 @default.
• W1909349784 cites W2020652522 @default.
• W1909349784 cites W2023925184 @default.
• W1909349784 cites W2026729241 @default.
• W1909349784 cites W2040661614 @default.
• W1909349784 cites W2041099687 @default.
• W1909349784 cites W2047593119 @default.
• W1909349784 cites W2076492225 @default.
• W1909349784 cites W2093767199 @default.
• W1909349784 cites W2106621186 @default.
• W1909349784 cites W2109814431 @default.
• W1909349784 cites W2111134819 @default.
• W1909349784 cites W2114785045 @default.
• W1909349784 cites W2117166221 @default.
• W1909349784 cites W2118489318 @default.
• W1909349784 cites W2126536749 @default.
• W1909349784 cites W2129716113 @default.
• W1909349784 cites W2134827411 @default.
• W1909349784 cites W2137563951 @default.
• W1909349784 cites W2142757379 @default.
• W1909349784 cites W2146558016 @default.
• W1909349784 cites W2148849112 @default.
• W1909349784 cites W2150428940 @default.
• W1909349784 cites W2154375528 @default.
• W1909349784 cites W2161872635 @default.
• W1909349784 cites W2165385153 @default.
• W1909349784 cites W2166734004 @default.
• W1909349784 doi "https://doi.org/10.1111/1469-0691.12312" @default.
• W1909349784 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23889746" @default.
• W1909349784 hasPublicationYear "2014" @default.
• W1909349784 type Work @default.
• W1909349784 sameAs 1909349784 @default.
• W1909349784 citedByCount "82" @default.
• W1909349784 countsByYear W19093497842014 @default.
• W1909349784 countsByYear W19093497842015 @default.
• W1909349784 countsByYear W19093497842016 @default.
• W1909349784 countsByYear W19093497842017 @default.
• W1909349784 countsByYear W19093497842018 @default.
• W1909349784 countsByYear W19093497842019 @default.
• W1909349784 countsByYear W19093497842020 @default.
• W1909349784 countsByYear W19093497842021 @default.
• W1909349784 countsByYear W19093497842022 @default.
• W1909349784 countsByYear W19093497842023 @default.
• W1909349784 crossrefType "journal-article" @default.
• W1909349784 hasAuthorship W1909349784A5006871789 @default.
• W1909349784 hasAuthorship W1909349784A5019102908 @default.
• W1909349784 hasAuthorship W1909349784A5037161493 @default.
• W1909349784 hasAuthorship W1909349784A5038285556 @default.
• W1909349784 hasAuthorship W1909349784A5040387230 @default.
• W1909349784 hasAuthorship W1909349784A5043593935 @default.
• W1909349784 hasAuthorship W1909349784A5045824682 @default.
• W1909349784 hasAuthorship W1909349784A5048001001 @default.
• W1909349784 hasAuthorship W1909349784A5050806596 @default.
• W1909349784 hasAuthorship W1909349784A5051047557 @default.
• W1909349784 hasAuthorship W1909349784A5054607147 @default.
• W1909349784 hasAuthorship W1909349784A5062566703 @default.
• W1909349784 hasAuthorship W1909349784A5065291460 @default.
• W1909349784 hasAuthorship W1909349784A5069171231 @default.
• W1909349784 hasAuthorship W1909349784A5070060458 @default.
• W1909349784 hasAuthorship W1909349784A5071800632 @default.
• W1909349784 hasAuthorship W1909349784A5078995254 @default.
• W1909349784 hasAuthorship W1909349784A5084278425 @default.
• W1909349784 hasAuthorship W1909349784A5085753272 @default.
• W1909349784 hasAuthorship W1909349784A5085951006 @default.
• W1909349784 hasAuthorship W1909349784A5086754307 @default.

• next