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• W1909551194 abstract "We report the cloning of the gyrB gene from Streptococcus pneumoniae 533 that carries the nov-1 allele. The gyrB gene codes for a protein homologous to the gyrase B subunit of archaebacteria and eubacteria. The same amino acid substitution (Ser-127 to Leu) confers novobiocin resistance on four isolates of S. pneumoniae. This amino acid position is equivalent to Val-120 of Escherichia coli GyrB, a residue that lies inside the ATP-binding domain as revealed by the crystal structure of the protein." @default.
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• W1909551194 date "1995-07-01" @default.
• W1909551194 modified "2023-10-13" @default.
• W1909551194 title "Ser-127-to-Leu substitution in the DNA gyrase B subunit of Streptococcus pneumoniae is implicated in novobiocin resistance" @default.
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• W1909551194 doi "https://doi.org/10.1128/jb.177.14.4166-4170.1995" @default.
• W1909551194 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/177155" @default.
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