FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1909748856> ?p ?o ?g. }

• W1909748856 endingPage "98" @default.
• W1909748856 startingPage "81" @default.
• W1909748856 abstract "Over the last decade, human neurodegenerative disorders which correlate with point mutations in mitochondrial tRNA genes became more and more numerous. Both the number of mutations (more than 70) and the variety of phenotypes (cardiopathies, myopathies, encephalopathies as well as diabetes, deafness or others) render the understanding of the genotype/phenotype relationships very complex. Here we first summarize the efforts undertaken to decipher the initial impact of various mutations on the structure/function relationships of tRNAs. This includes several lines of research, namely (i) investigation of human mitochrondrial tRNA structures, (ii) comparison of disease-related and polymorphic mutations at a theoretical level, and (iii) experimental investigations of affected tRNAs in the frame of mitochondrial protein synthesis. A new approach aimed at searching for long-range effects of mitochondrial tRNA mutations on a broader global mitochondrial level will also be presented. Initial results obtained by comparative mitochondrial proteomics turn out to be very promising for deciphering unexpected molecular partners involved in the pathological status of the mitochondria." @default.
• W1909748856 created "2016-06-24" @default.
• W1909748856 creator A5088580567 @default.
• W1909748856 date "2002-02-01" @default.
• W1909748856 modified "2023-10-18" @default.
• W1909748856 title "Molecular Investigations on tRNAs Involved in Human Mitochondrial Disorders" @default.
• W1909748856 cites W1490199160 @default.
• W1909748856 cites W1520694472 @default.
• W1909748856 cites W1544552427 @default.
• W1909748856 cites W1765516395 @default.
• W1909748856 cites W1859693382 @default.
• W1909748856 cites W1877954338 @default.
• W1909748856 cites W1899924400 @default.
• W1909748856 cites W1908757304 @default.
• W1909748856 cites W1965253821 @default.
• W1909748856 cites W1973844953 @default.
• W1909748856 cites W1974538162 @default.
• W1909748856 cites W197559234 @default.
• W1909748856 cites W1979951442 @default.
• W1909748856 cites W1980055846 @default.
• W1909748856 cites W1982151076 @default.
• W1909748856 cites W2000111317 @default.
• W1909748856 cites W2005400653 @default.
• W1909748856 cites W2020988283 @default.
• W1909748856 cites W2025757976 @default.
• W1909748856 cites W2027190461 @default.
• W1909748856 cites W2028428630 @default.
• W1909748856 cites W2039243132 @default.
• W1909748856 cites W2040118814 @default.
• W1909748856 cites W2043779724 @default.
• W1909748856 cites W2044494908 @default.
• W1909748856 cites W2045409504 @default.
• W1909748856 cites W2049948858 @default.
• W1909748856 cites W2051951720 @default.
• W1909748856 cites W2053732071 @default.
• W1909748856 cites W2053919301 @default.
• W1909748856 cites W2056174109 @default.
• W1909748856 cites W2057892106 @default.
• W1909748856 cites W2063222273 @default.
• W1909748856 cites W2065660771 @default.
• W1909748856 cites W2069169076 @default.
• W1909748856 cites W2074934195 @default.
• W1909748856 cites W2075072811 @default.
• W1909748856 cites W2075835114 @default.
• W1909748856 cites W2078991180 @default.
• W1909748856 cites W2080211953 @default.
• W1909748856 cites W2080711087 @default.
• W1909748856 cites W2082144941 @default.
• W1909748856 cites W2084323021 @default.
• W1909748856 cites W2089802962 @default.
• W1909748856 cites W2093282886 @default.
• W1909748856 cites W2093769391 @default.
• W1909748856 cites W2106311383 @default.
• W1909748856 cites W2109291482 @default.
• W1909748856 cites W2115054680 @default.
• W1909748856 cites W2124207622 @default.
• W1909748856 cites W2130460780 @default.
• W1909748856 cites W2137748756 @default.
• W1909748856 cites W2141009329 @default.
• W1909748856 cites W2143988400 @default.
• W1909748856 cites W2147540988 @default.
• W1909748856 cites W2157470390 @default.
• W1909748856 cites W2162288115 @default.
• W1909748856 cites W2165676560 @default.
• W1909748856 cites W2167673850 @default.
• W1909748856 cites W2170305696 @default.
• W1909748856 cites W2269680447 @default.
• W1909748856 cites W408505 @default.
• W1909748856 cites W651022058 @default.
• W1909748856 cites W946255440 @default.
• W1909748856 doi "https://doi.org/10.1023/a:1016065107165" @default.
• W1909748856 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12418552" @default.
• W1909748856 hasPublicationYear "2002" @default.
• W1909748856 type Work @default.
• W1909748856 sameAs 1909748856 @default.
• W1909748856 citedByCount "23" @default.
• W1909748856 countsByYear W19097488562012 @default.
• W1909748856 countsByYear W19097488562013 @default.
• W1909748856 countsByYear W19097488562014 @default.
• W1909748856 countsByYear W19097488562016 @default.
• W1909748856 countsByYear W19097488562020 @default.
• W1909748856 countsByYear W19097488562021 @default.
• W1909748856 crossrefType "journal-article" @default.
• W1909748856 hasAuthorship W1909748856A5088580567 @default.
• W1909748856 hasBestOaLocation W19097488562 @default.
• W1909748856 hasConcept C104317684 @default.
• W1909748856 hasConcept C127716648 @default.
• W1909748856 hasConcept C151994961 @default.
• W1909748856 hasConcept C153957851 @default.
• W1909748856 hasConcept C176944494 @default.
• W1909748856 hasConcept C24586158 @default.
• W1909748856 hasConcept C2775833069 @default.
• W1909748856 hasConcept C2777614518 @default.
• W1909748856 hasConcept C28859421 @default.
• W1909748856 hasConcept C501734568 @default.
• W1909748856 hasConcept C54355233 @default.
• W1909748856 hasConcept C67705224 @default.
• W1909748856 hasConcept C70721500 @default.

• next