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- W1909875144 abstract "Pantoea stewartii subsp. stewartii is the etiological agent of Stewart’s wilt and is a serious bacterial pathogen affecting sweet corn. During the leaf blight phase, P. stewartii colonizes the leaf apoplast and causes a characteristic water-soaked lesion. The Hrp type III secretion system has been implicated in the water-soaking phenotype, and the goal of this study was to investigate other potential factors that contribute to the plant cellular disruption associated with these lesions. The P. stewartii genome contains a gene encoding a large repetitive RTX toxin, designated rtx2. RTX toxins comprise a large family of pore-forming proteins, which are widely distributed among gram-negative bacteria. These cytotoxins usually lyse their target host cells and cause significant tissue damage as a consequence. We hypothesized that this RTX-like toxin plays a role in the water-soaking phase of infection due to its predicted cytolytic properties. Based on the data reported here, we conclude that RTX2 contributes significantly to the development of water-soaked lesions and leakage of plant cellular contents and is an important pathogenicity factor for P. stewartii." @default.
- W1909875144 created "2016-06-24" @default.
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- W1909875144 date "2015-12-01" @default.
- W1909875144 modified "2023-10-10" @default.
- W1909875144 title "A Large Repetitive RTX-Like Protein Mediates Water-Soaked Lesion Development, Leakage of Plant Cell Content and Host Colonization in the <i>Pantoea stewartii</i> subsp. <i>stewartii</i> Pathosystem" @default.
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- W1909875144 doi "https://doi.org/10.1094/mpmi-05-15-0109-r" @default.
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