Matches in SemOpenAlex for { <https://semopenalex.org/work/W1910305918> ?p ?o ?g. }
- W1910305918 endingPage "112" @default.
- W1910305918 startingPage "96" @default.
- W1910305918 abstract "Summary The RNAi machinery is generally involved in genome protection in filamentous fungi; however, the physiological role of RNAi has been poorly studied in fungal models. Here, we report that in the filamentous fungus T richoderma atroviride , the products of the dcr2 and rdr3 genes control reproductive development, because mutations in these genes affect conidiation. In addition, Dcr1 together with Dcr2 control vegetative growth since Δ dcr1 , Δ dcr2 and Δ dcr1 Δ dcr2 present morphological alterations. Whole‐genome transcriptional analysis of WT , Δ dcr1 , Δ dcr2 and Δ dcr1 Δ dcr2 show that each Dicer controls different biological processes, such as development or metabolism, which could explain the lack of conidiation in the mutants. Finally, we observed sRNAs that are differentially expressed in the WT and Δ dcr2 . The expression of some of these sRNAs correlates with the expression of differential transcripts, suggesting that these mRNAs may contain the corresponding targets. Together these data show that in T . atroviride , the RNAi machinery plays a central role in endogenous processes such as development and fitness, beyond controlling genome protection against invasive nucleic acids as reported for other fungi." @default.
- W1910305918 created "2016-06-24" @default.
- W1910305918 creator A5004095859 @default.
- W1910305918 creator A5014947740 @default.
- W1910305918 creator A5018362137 @default.
- W1910305918 creator A5060302506 @default.
- W1910305918 creator A5081612525 @default.
- W1910305918 date "2013-06-07" @default.
- W1910305918 modified "2023-10-03" @default.
- W1910305918 title "The RNAi machinery regulates growth and development in the filamentous fungus<i>Trichoderma atroviride</i>" @default.
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