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- W1910516945 abstract "After the oral administration of sodium pentobarbital (Nembutal) labeled with N 15 , dogs excreted about 60% of the total dose of excess N 15 in the urine during the first 24 hours. The excess N 15 in the urinary ammonia and urea represented less than 8% of the N 15 so that more than 92% was excreted as pentobarbital or metabolic degradation products derived from the drug. In one isotope-dilution experiment, about 3% of the total excess N 15 in the urine was found to be pentobarbital; this finding confirms the conclusion of other investigators that only minute amounts of pentobarbital are excreted unchanged. Possible structures of the major excretion product or products remain to be considered." @default.
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- W1910516945 date "1947-08-01" @default.
- W1910516945 modified "2023-09-23" @default.
- W1910516945 title "THE EXCRETION OF N15 IN THE URINE OF DOGS AFTER THE ADMINISTRATION OF LABELED PENTOBARBITAL" @default.
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