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- W1911464812 abstract "Increased serum levels of liver enzymes have been reported in patients with obstructive sleep apnea (OSA), but the prevalence of liver dysfunction in OSA is poorly defined. In 91 consecutive patients (23 females) without serological evidence of viral hepatitis or alcohol-induced liver disease who underwent nocturnal respiratory monitoring for diagnosis of OSA, we measured alanine (ALT) and aspartate (AST) aminotransferase, and gamma-glutamyltransferase (GGT) in serum, together with the HOMA Index and the lipid profile. Mean age and BMI were 55±14 (SD) yr, and 37.4±8.4 kg/m 2 , respectively. OSA was moderate to severe (mean AHI 49±24/h, lowest SaO 2 69.3±12.8%). Increased ALT or AST (≥41 IU/L) was found in 11 and 5 patients (12% and 5.5%), respectively. Compared to patients with normal ALT levels, patients with elevated ALT were significantly younger (43.2±5.5 vs 56.4±14.3 yr, p Funding by Italian Ministry of University and Research (PRIN 200895H8S9)" @default.
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- W1911464812 date "2011-09-01" @default.
- W1911464812 modified "2023-09-28" @default.
- W1911464812 title "Markers of liver dysfunction in patients with obstructive sleep apnea" @default.
- W1911464812 hasPublicationYear "2011" @default.
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