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- W1912124796 endingPage "425" @default.
- W1912124796 startingPage "409" @default.
- W1912124796 abstract "Radiotherapy plays a central part in curing cancer. For decades, most research on improving treatment outcomes has focused on modulating radiation-induced biological effects on cancer cells. Recently, we have better understood that components within the tumour microenvironment have pivotal roles in determining treatment outcomes. In this Review, we describe vascular, stromal and immunological changes that are induced in the tumour microenvironment by irradiation and discuss how these changes may promote radioresistance and tumour recurrence. We also highlight how this knowledge is guiding the development of new treatment paradigms in which biologically targeted agents will be combined with radiotherapy." @default.
- W1912124796 created "2016-06-24" @default.
- W1912124796 creator A5017608904 @default.
- W1912124796 creator A5037970330 @default.
- W1912124796 creator A5072284989 @default.
- W1912124796 creator A5076395478 @default.
- W1912124796 date "2015-06-24" @default.
- W1912124796 modified "2023-10-18" @default.
- W1912124796 title "The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence" @default.
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