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- W1912881503 abstract "(CP-62,993) more active than erythromycin but not as active as ciprofloxacin on 300 strains of N. gonorrhoeae (100 from Winnipeg, 200 from Nairobi including 100 PPNG). With present interest about rising levels of syphilis in USA, azithromycin has been shown to be effective as therapy of active syphilis in the rabbit modeltl12. Toxoplasma gondii has been highlighted as an opportunistic infection in HIV disease. Azithromycij-, has been shown to be effective in murine experiments from California and Europe13l5 • What evidence is there that azithromycin is effective for sexually transmitted diseases from clinical studies? Unto now there have been 2 main studies on STD (gonorrhoea, C. trachomaiis, U. urealyticum). Interpretation of results is complicated owing to various dosage regimens. Steingrimsson et al.16 in a trial of 168 patients in Reykjavik, treated 113 patients with azithromycin and 55 with doxycycline where isolates were found to be 138 C. trachomatis, 43 N. gonorrhoeae, 45 U. urealyticum, a 96%cure rate was claimed for C. trachomatis and 92% for gonorrhoea with azithromycin. However, they also noted that 2 patients from whom N. gonorrhoeae, 4 from whom C. trachomatis and 6 from whom" @default.
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- W1912881503 date "1991-07-01" @default.
- W1912881503 modified "2023-09-27" @default.
- W1912881503 title "Azithromycin in Sexually Transmitted Diseases—An Overview" @default.
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- W1912881503 doi "https://doi.org/10.1177/095646249100200403" @default.
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