FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1912978047> ?p ?o ?g. }

• W1912978047 endingPage "1121" @default.
• W1912978047 startingPage "1115" @default.
• W1912978047 abstract "Expressed on various cell types, the IL-4Ralpha is a component of both receptors for IL-4 and IL-13. Susceptibility of BALB/c mice to Leishmania major is believed to be dependent on the development of IL-4- and IL-13-producing Th2 cells, while IFN-gamma secretion by Th1 cells is related to resistance. Despite a sustained development of Th2 cells, IL-4Ralpha-deficient BALB/c mice are able to control acute cutaneous leishmaniasis, suggesting that IL-4Ralpha-bearing cells other than Th2 cells contribute to susceptibility. To analyze the contribution of the IL-4Ralpha on macrophages, recently generated macrophage/neutrophil-specific IL-4Ralpha-deficient mice on a susceptible BALB/c genetic background were infected with L. major. Strikingly, macrophage/neutrophil-specific IL-4Ralpha-deficient mice showed a significantly delayed disease progression with normal Th2 and type 2 Ab responses but improved macrophage leishmanicidal effector functions and reduced arginase activity. Together, these results suggest that alternative macrophage activation contributes to susceptibility in cutaneous leishmaniasis." @default.
• W1912978047 created "2016-06-24" @default.
• W1912978047 creator A5002941720 @default.
• W1912978047 creator A5008565163 @default.
• W1912978047 creator A5027424579 @default.
• W1912978047 creator A5048518247 @default.
• W1912978047 creator A5067536098 @default.
• W1912978047 date "2006-01-15" @default.
• W1912978047 modified "2023-10-11" @default.
• W1912978047 title "Impairment of Alternative Macrophage Activation Delays Cutaneous Leishmaniasis in Nonhealing BALB/c Mice" @default.
• W1912978047 cites W1492030666 @default.
• W1912978047 cites W1526905466 @default.
• W1912978047 cites W1562312254 @default.
• W1912978047 cites W1579584019 @default.
• W1912978047 cites W1595293335 @default.
• W1912978047 cites W1834954945 @default.
• W1912978047 cites W1855297813 @default.
• W1912978047 cites W1875764398 @default.
• W1912978047 cites W1943484616 @default.
• W1912978047 cites W1968904011 @default.
• W1912978047 cites W1986367263 @default.
• W1912978047 cites W1987909356 @default.
• W1912978047 cites W1988128973 @default.
• W1912978047 cites W2006318766 @default.
• W1912978047 cites W2015681660 @default.
• W1912978047 cites W2022775599 @default.
• W1912978047 cites W2023942616 @default.
• W1912978047 cites W2027464430 @default.
• W1912978047 cites W2038425317 @default.
• W1912978047 cites W2038689279 @default.
• W1912978047 cites W2067049479 @default.
• W1912978047 cites W2081973949 @default.
• W1912978047 cites W2087437823 @default.
• W1912978047 cites W2104032278 @default.
• W1912978047 cites W2116394003 @default.
• W1912978047 cites W2116797822 @default.
• W1912978047 cites W2122158599 @default.
• W1912978047 cites W2123661985 @default.
• W1912978047 cites W2136415390 @default.
• W1912978047 cites W2143157380 @default.
• W1912978047 cites W2146213573 @default.
• W1912978047 cites W2153930422 @default.
• W1912978047 cites W2163414629 @default.
• W1912978047 cites W2163925698 @default.
• W1912978047 cites W2166519885 @default.
• W1912978047 cites W2168360174 @default.
• W1912978047 cites W2168930459 @default.
• W1912978047 cites W4313305992 @default.
• W1912978047 cites W4313332019 @default.
• W1912978047 doi "https://doi.org/10.4049/jimmunol.176.2.1115" @default.
• W1912978047 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16394000" @default.
• W1912978047 hasPublicationYear "2006" @default.
• W1912978047 type Work @default.
• W1912978047 sameAs 1912978047 @default.
• W1912978047 citedByCount "103" @default.
• W1912978047 countsByYear W19129780472012 @default.
• W1912978047 countsByYear W19129780472013 @default.
• W1912978047 countsByYear W19129780472014 @default.
• W1912978047 countsByYear W19129780472015 @default.
• W1912978047 countsByYear W19129780472016 @default.
• W1912978047 countsByYear W19129780472017 @default.
• W1912978047 countsByYear W19129780472018 @default.
• W1912978047 countsByYear W19129780472019 @default.
• W1912978047 countsByYear W19129780472020 @default.
• W1912978047 countsByYear W19129780472021 @default.
• W1912978047 countsByYear W19129780472022 @default.
• W1912978047 countsByYear W19129780472023 @default.
• W1912978047 crossrefType "journal-article" @default.
• W1912978047 hasAuthorship W1912978047A5002941720 @default.
• W1912978047 hasAuthorship W1912978047A5008565163 @default.
• W1912978047 hasAuthorship W1912978047A5027424579 @default.
• W1912978047 hasAuthorship W1912978047A5048518247 @default.
• W1912978047 hasAuthorship W1912978047A5067536098 @default.
• W1912978047 hasBestOaLocation W19129780471 @default.
• W1912978047 hasConcept C136764020 @default.
• W1912978047 hasConcept C202751555 @default.
• W1912978047 hasConcept C203014093 @default.
• W1912978047 hasConcept C2779244956 @default.
• W1912978047 hasConcept C2780599195 @default.
• W1912978047 hasConcept C2781092759 @default.
• W1912978047 hasConcept C41008148 @default.
• W1912978047 hasConcept C51785407 @default.
• W1912978047 hasConcept C54355233 @default.
• W1912978047 hasConcept C71924100 @default.
• W1912978047 hasConcept C71928629 @default.
• W1912978047 hasConcept C86803240 @default.
• W1912978047 hasConceptScore W1912978047C136764020 @default.
• W1912978047 hasConceptScore W1912978047C202751555 @default.
• W1912978047 hasConceptScore W1912978047C203014093 @default.
• W1912978047 hasConceptScore W1912978047C2779244956 @default.
• W1912978047 hasConceptScore W1912978047C2780599195 @default.
• W1912978047 hasConceptScore W1912978047C2781092759 @default.
• W1912978047 hasConceptScore W1912978047C41008148 @default.
• W1912978047 hasConceptScore W1912978047C51785407 @default.
• W1912978047 hasConceptScore W1912978047C54355233 @default.
• W1912978047 hasConceptScore W1912978047C71924100 @default.
• W1912978047 hasConceptScore W1912978047C71928629 @default.
• W1912978047 hasConceptScore W1912978047C86803240 @default.

• next