Matches in SemOpenAlex for { <https://semopenalex.org/work/W1914605493> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1914605493 endingPage "329" @default.
- W1914605493 startingPage "323" @default.
- W1914605493 abstract "The hepatic microsomal haem oxygenase activity of rats treated with CoCl2 was studied kinetically by measuring biliverdin, the immediate product of the reaction. Biliverdin was extracted with diethyl ether/ethanol mixture, and was determined by the difference between A690 and A800. The apparent Km value for NADPH (at 50 microM-haematin) was about 0.2 microM when an NADPH-generating system was used, whereas that for NADH was about 630 microM. Essentially the same Vmax. values were obtained for both the NADH- and NADPH-dependent haem oxygenase reactions. No synergism was observed with NADH and NADPH. The NADH-dependent reaction was competitively inhibited by NADP+, with a Ki of about 10 microM. The inhibitoin of the NADH-dependent reaction by the antibody against rat liver microsomal NADPH-cytochrome c reductase was essentially complete, with a pattern similar to that of the NADPH-dependent reaction. The immunochemical experiment and the comparison of the kinetic values with the reported data on isolated NADH-cytochrome b5 reductase and NADPH–cytochrome c reductase indicated the involvement of the latter enzyme in NADH-dependent haem oxygenation by microsomal fraction in situ." @default.
- W1914605493 created "2016-06-24" @default.
- W1914605493 creator A5002479841 @default.
- W1914605493 creator A5065421754 @default.
- W1914605493 date "1979-02-15" @default.
- W1914605493 modified "2023-09-23" @default.
- W1914605493 title "Electron-transport pathway of the NADH-dependent haem oxygenase system of rat liver microsomal fraction induced by cobalt chloride" @default.
- W1914605493 cites W1205458192 @default.
- W1914605493 cites W1480025749 @default.
- W1914605493 cites W1498049218 @default.
- W1914605493 cites W1591521631 @default.
- W1914605493 cites W1639043875 @default.
- W1914605493 cites W1775749144 @default.
- W1914605493 cites W1964479613 @default.
- W1914605493 cites W2007880418 @default.
- W1914605493 cites W2028778467 @default.
- W1914605493 cites W2037078665 @default.
- W1914605493 cites W2122425601 @default.
- W1914605493 cites W2402108407 @default.
- W1914605493 cites W2405915917 @default.
- W1914605493 cites W2409770896 @default.
- W1914605493 cites W2513210861 @default.
- W1914605493 doi "https://doi.org/10.1042/bj1780323" @default.
- W1914605493 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1186518" @default.
- W1914605493 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36076" @default.
- W1914605493 hasPublicationYear "1979" @default.
- W1914605493 type Work @default.
- W1914605493 sameAs 1914605493 @default.
- W1914605493 citedByCount "13" @default.
- W1914605493 crossrefType "journal-article" @default.
- W1914605493 hasAuthorship W1914605493A5002479841 @default.
- W1914605493 hasAuthorship W1914605493A5065421754 @default.
- W1914605493 hasBestOaLocation W19146054932 @default.
- W1914605493 hasConcept C134651460 @default.
- W1914605493 hasConcept C165474305 @default.
- W1914605493 hasConcept C181199279 @default.
- W1914605493 hasConcept C185592680 @default.
- W1914605493 hasConcept C20705724 @default.
- W1914605493 hasConcept C23849879 @default.
- W1914605493 hasConcept C2776217839 @default.
- W1914605493 hasConcept C2779219270 @default.
- W1914605493 hasConcept C2780768313 @default.
- W1914605493 hasConcept C55493867 @default.
- W1914605493 hasConcept C71240020 @default.
- W1914605493 hasConcept C75520062 @default.
- W1914605493 hasConcept C87644729 @default.
- W1914605493 hasConceptScore W1914605493C134651460 @default.
- W1914605493 hasConceptScore W1914605493C165474305 @default.
- W1914605493 hasConceptScore W1914605493C181199279 @default.
- W1914605493 hasConceptScore W1914605493C185592680 @default.
- W1914605493 hasConceptScore W1914605493C20705724 @default.
- W1914605493 hasConceptScore W1914605493C23849879 @default.
- W1914605493 hasConceptScore W1914605493C2776217839 @default.
- W1914605493 hasConceptScore W1914605493C2779219270 @default.
- W1914605493 hasConceptScore W1914605493C2780768313 @default.
- W1914605493 hasConceptScore W1914605493C55493867 @default.
- W1914605493 hasConceptScore W1914605493C71240020 @default.
- W1914605493 hasConceptScore W1914605493C75520062 @default.
- W1914605493 hasConceptScore W1914605493C87644729 @default.
- W1914605493 hasIssue "2" @default.
- W1914605493 hasLocation W19146054931 @default.
- W1914605493 hasLocation W19146054932 @default.
- W1914605493 hasLocation W19146054933 @default.
- W1914605493 hasLocation W19146054934 @default.
- W1914605493 hasOpenAccess W1914605493 @default.
- W1914605493 hasPrimaryLocation W19146054931 @default.
- W1914605493 hasRelatedWork W1530961659 @default.
- W1914605493 hasRelatedWork W184984524 @default.
- W1914605493 hasRelatedWork W1914605493 @default.
- W1914605493 hasRelatedWork W1987906593 @default.
- W1914605493 hasRelatedWork W1997514276 @default.
- W1914605493 hasRelatedWork W2008209363 @default.
- W1914605493 hasRelatedWork W2065101979 @default.
- W1914605493 hasRelatedWork W2147361124 @default.
- W1914605493 hasRelatedWork W2148808058 @default.
- W1914605493 hasRelatedWork W2152255439 @default.
- W1914605493 hasVolume "178" @default.
- W1914605493 isParatext "false" @default.
- W1914605493 isRetracted "false" @default.
- W1914605493 magId "1914605493" @default.
- W1914605493 workType "article" @default.