FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1914869509> ?p ?o ?g. }

• W1914869509 abstract "Sir,Dengue fever (DF) is an acute febrile illness found in the tropics, caused by four antigenically related, but distinct viruses viz., DEN-1, DEN-2, DEN-3 and DEN-4 classified under genus Flavivirus, Family Flaviviridae. Dengue is transmitted to humans through the bites of day biting Aedes aegypti. All four serotypes induce a spectrum of illness, ranging from sudden onset of fever, and head ache often accompanied by myalgia, anorexia, arthralgia to increased vascular permeability in dengue haemorrhagic fever (DHF). DF/DHF is confined to the tropics and sub-tropics. Dengue virus infection occurs in >100 countries; with >2.5 billion persons living in these areas. During the past decades, dengue virus has emerged in southern Asia; DF/DHF epidemics have occurred in South East Asia Region (SEAR)1,2. However, dengue has not been reported in Andaman and Nicobar archipelago6.Andaman and Nicobar islands (92° to 94° East and 6° to 14° North), is an archipelago with > 500 islands/islets, stretching over 700 km from north to south, in the Bay of Bengal. There are 38 inhabited islands with a population of approximately 356,0003. People constantly move between these islands and mainland India, connected by ship and air to Chennai and Kolkata. Periodic outbreaks of dengue fever have been reported in these port cities4,5. Tourism industry is witnessing a significant surge in the number of tourists from mainland India as well as from overseas.From June through July 2009, we observed an increase in the number of dengue like febrile patients from G.B. Pant Hospital, referral hospital in these islands and from a private child care clinic located in Port Blair. Clinical features in most of the patients were consistent with signs of DF7. Blood specimens were collected from suspected patients at the time of admission and sent to the Regional Medical Research Centre (ICMR), for laboratory diagnosis. All were tested for the presence of anti-dengue virus (DENV) immunoglobulin M (IgM) antibody and anti-chikungunya virus IgM antibody by IgM capture ELISA method by the kits developed by National Institute of Virology (NIV), Pune8. Blood samples were collected between 3-5 days post onset of signs. A total of 101 patients were admitted to hospital/child care/health centres. Dengue virus specific IgM was detected in 26 patients. Suspected and confirmed patients of DF/DHF/DSS (dengue shock syndrome) in different age groups are shown in the Table. Among the patients suspected to be of DHF and DSS, tourniquet test was positive and platelet count was < 100000/mm3. Clinical features and laboratory test findings were consistent with the WHO guidelines7. None of the patients had history of travel to the mainland, or any other dengue endemic countries. All patients were negative for chikungunya virus infection. Concurrently, entomological survey was carried out in one of the locality viz., Garacharma reporting suspected cases. The basic sampling unit was a household, which was systematically searched for water holding containers. Premises were searched, in both indoors and outdoors. Single larval survey (SLS) technique was adopted to assess the larval infestation indices and prevalence of Aedes spp.9. The immatures from different habitats were collected with the help of ladles fabricated with long handles and with glass pipettes where ladles did not enter. Three indices commonly used to assess relative prevalence and monitor Ae. aegypti infestation levels viz., the Breteau index (BI), container index (CI) and house index (HI) were assessed. The BI establishes a relationship between positive containers and houses; CI provides information on the proportion of water holding containers that are positive, while the HI provides information on the proportion of houses positive for the immature larvae9. The immature larvae sampled from different habitats were transferred to plastic containers and were brought to the Centre's laboratory and reared individually in plastic vials up to the emergence of adult. The adults were identified to species10.TableSuspected and confirmed patients of dengue fever/DHF/DHF with shock among different age groupsA total of 147 households were searched randomly. As many as 1001 (mean = 6.81 containers per premise) water holding containers were searched for Aedes larvae, both indoors (143/1001, 14.29%) and outdoors (858/1001, 85.71%); 127 containers (95% CI = 10.73%-14.86%) were found to support Aedes spp. larval breeding (12.69%). Breteau index was 86.39 per cent. From the 127 mosquito immatures emerged, Ae. aegypti (112/127, 88.2%) predominantly followed by Ae. albopictus (15/127, 11.8%). HI for Ae. aegypti and Ae. albopictus were 35.37 and 7.48 per cent respectively. Abundant water holding containers supporting Aedes breeding were cement tanks, metal and plastic drums.The observations of clinical dengue, DHF and DSS supported by evidence for recent infections are perhaps the first ever from this archipelago. DHF appears when more than one serotype circulates in an area11. Reasons for emergence of DF/DHF are complex. However, plausible factors that appear to have contributed to the present scenario can be identified. First, demographic changes, most importantly rapid urbanization and population growth, eventually leading to inadequate water, necessitating storage of water in containers, this leads to increase in Ae. aegypti population densities facilitating transmission. Second, domestic/peri-domestic breeding of mosquitoes contained significant numbers of Ae. aegypti vis-a-vis Ae. albopictus with high larval indices; abundance of a particular species is considered as one criterion for determining the vector status. Finally, increased air travel serves transportation of dengue viruses between endemic locations on the mainland.Ever since the documentation of prevalence of antibodies for dengue fever (DEN-2) in these islands12, the health personnel in the islands have been keeping a vigil on the emergence of disease. During the 2006 chikungunya epidemic6 over 150 subjects were tested for dengue fever and none turned positive.Ae . aegypti has a wide distribution within urban Port Blair13 and is infiltrating to other peri-urban/rural areas14. Consequently, the adjoining peri-urban and rural areas are receptive to DENV. Therefore, continued risk of dengue infection cannot be ignored. Besides, inadequate health infrastructure with competing priorities, geographical remoteness of the areas within island, promotion of Andaman and Nicobar archipelago as an international tourist destination, DF/DHF is an emerging problem. Moreover, it is known that DHF occurs where multiple serotypes of dengue virus are simultaneously or sequentially transmitted11. Current situation warrants extreme vigil from public health perspective for its effective control." @default.
• W1914869509 created "2016-06-24" @default.
• W1914869509 creator A5013633367 @default.
• W1914869509 creator A5022986073 @default.
• W1914869509 creator A5034357413 @default.
• W1914869509 creator A5041134494 @default.
• W1914869509 creator A5043249592 @default.
• W1914869509 creator A5052785712 @default.
• W1914869509 creator A5062560084 @default.
• W1914869509 creator A5062819311 @default.
• W1914869509 creator A5076835559 @default.
• W1914869509 date "2011-08-01" @default.
• W1914869509 modified "2023-09-27" @default.
• W1914869509 title "Emergence of dengue in Andaman & Nicobar archipelago: eco-epidemiological perspective." @default.
• W1914869509 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3181026" @default.
• W1914869509 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21911978" @default.
• W1914869509 hasPublicationYear "2011" @default.
• W1914869509 type Work @default.
• W1914869509 sameAs 1914869509 @default.
• W1914869509 citedByCount "8" @default.
• W1914869509 countsByYear W19148695092014 @default.
• W1914869509 countsByYear W19148695092015 @default.
• W1914869509 countsByYear W19148695092017 @default.
• W1914869509 countsByYear W19148695092018 @default.
• W1914869509 countsByYear W19148695092019 @default.
• W1914869509 crossrefType "posted-content" @default.
• W1914869509 hasAuthorship W1914869509A5013633367 @default.
• W1914869509 hasAuthorship W1914869509A5022986073 @default.
• W1914869509 hasAuthorship W1914869509A5034357413 @default.
• W1914869509 hasAuthorship W1914869509A5041134494 @default.
• W1914869509 hasAuthorship W1914869509A5043249592 @default.
• W1914869509 hasAuthorship W1914869509A5052785712 @default.
• W1914869509 hasAuthorship W1914869509A5062560084 @default.
• W1914869509 hasAuthorship W1914869509A5062819311 @default.
• W1914869509 hasAuthorship W1914869509A5076835559 @default.
• W1914869509 hasConcept C107130276 @default.
• W1914869509 hasConcept C126322002 @default.
• W1914869509 hasConcept C12713177 @default.
• W1914869509 hasConcept C159047783 @default.
• W1914869509 hasConcept C18903297 @default.
• W1914869509 hasConcept C204207459 @default.
• W1914869509 hasConcept C205649164 @default.
• W1914869509 hasConcept C2524010 @default.
• W1914869509 hasConcept C2779635636 @default.
• W1914869509 hasConcept C33923547 @default.
• W1914869509 hasConcept C505870484 @default.
• W1914869509 hasConcept C533803919 @default.
• W1914869509 hasConcept C71924100 @default.
• W1914869509 hasConcept C86803240 @default.
• W1914869509 hasConcept C90856448 @default.
• W1914869509 hasConceptScore W1914869509C107130276 @default.
• W1914869509 hasConceptScore W1914869509C126322002 @default.
• W1914869509 hasConceptScore W1914869509C12713177 @default.
• W1914869509 hasConceptScore W1914869509C159047783 @default.
• W1914869509 hasConceptScore W1914869509C18903297 @default.
• W1914869509 hasConceptScore W1914869509C204207459 @default.
• W1914869509 hasConceptScore W1914869509C205649164 @default.
• W1914869509 hasConceptScore W1914869509C2524010 @default.
• W1914869509 hasConceptScore W1914869509C2779635636 @default.
• W1914869509 hasConceptScore W1914869509C33923547 @default.
• W1914869509 hasConceptScore W1914869509C505870484 @default.
• W1914869509 hasConceptScore W1914869509C533803919 @default.
• W1914869509 hasConceptScore W1914869509C71924100 @default.
• W1914869509 hasConceptScore W1914869509C86803240 @default.
• W1914869509 hasConceptScore W1914869509C90856448 @default.
• W1914869509 hasLocation W19148695091 @default.
• W1914869509 hasOpenAccess W1914869509 @default.
• W1914869509 hasPrimaryLocation W19148695091 @default.
• W1914869509 hasRelatedWork W101491854 @default.
• W1914869509 hasRelatedWork W1963663951 @default.
• W1914869509 hasRelatedWork W1990399369 @default.
• W1914869509 hasRelatedWork W1999909784 @default.
• W1914869509 hasRelatedWork W2007125803 @default.
• W1914869509 hasRelatedWork W2032265612 @default.
• W1914869509 hasRelatedWork W2035229593 @default.
• W1914869509 hasRelatedWork W2048323350 @default.
• W1914869509 hasRelatedWork W2094091907 @default.
• W1914869509 hasRelatedWork W2149868134 @default.
• W1914869509 hasRelatedWork W2154659849 @default.
• W1914869509 hasRelatedWork W2166764154 @default.
• W1914869509 hasRelatedWork W2267222107 @default.
• W1914869509 hasRelatedWork W2414522988 @default.
• W1914869509 hasRelatedWork W2415204306 @default.
• W1914869509 hasRelatedWork W28269071 @default.
• W1914869509 hasRelatedWork W69836725 @default.
• W1914869509 hasRelatedWork W92308610 @default.
• W1914869509 hasRelatedWork W2167390792 @default.
• W1914869509 hasRelatedWork W2411773710 @default.
• W1914869509 isParatext "false" @default.
• W1914869509 isRetracted "false" @default.
• W1914869509 magId "1914869509" @default.
• W1914869509 workType "article" @default.