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- W1914961657 abstract "Background L-alpha-Melanocortin is a strong inhibitor of inflammation. It is a promising new anti-inflammatory and hepatoprotective peptide. Consequently, its melanocortin receptors (MC1, MC3, MC4 and MC5) could be possible targets for the development of new antiinflammatory drugs for chronic inflammatory liver disease. For a long time it has been believed that only the L-enantiomers of amino acids are present in higher animals, but recent investigations show that D-amino acids also exhibit physiological effects in vivo, despite their very small quantities. The aim of this study was to compare hepatoprotective effects of L-alpha-melanocortin and D-alpha-melanocortin using the acetaminophen model of chemical liver damage in male CBA mice." @default.
- W1914961657 created "2016-06-24" @default.
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- W1914961657 date "2012-09-01" @default.
- W1914961657 modified "2023-10-10" @default.
- W1914961657 title "The influence of alpha-melanocortin enantiomers on acetaminophen-induced hepatis in mice" @default.
- W1914961657 doi "https://doi.org/10.1186/2050-6511-13-s1-a77" @default.
- W1914961657 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3506344" @default.
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