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• W1915150039 abstract "The incidence of heart failure continues to rise in western countries. The social and economic impact that congestive heart failure has on society is underscored by its prevalence, morbidity and mortality rates, lost wages, and cost for care. As the population ages and western standards of living are widely adopted by more countries, the incidence of congestive heart failure might reach, in the next few decades, epidemic levels. Coronary artery disease and hypertension remain the two most common causes for left ventricular systolic and diastolic dysfunction and chronic obstructive lung disease for isolated right ventricular failure in Europe and North America. In western countries the prevention of heart failure is based on effective primary prevention of coronary artery disease, lung disease, and on the concerted effort to timely and aggressively treat hyperlipidemia and hypertension, discontinue smoking, increase physical activity, and reduce obesity. Unfortunately while these risk factors have been widely publicized and should be well known to the general population, dramatic lifestyle changes have not yet occurred. In fact, recent discouraging reports indicate an increase in the incidence of obesity and cigarette smoking, and decrease in physical activity among adolescents. 1 Kelder S.H. Perry C.L. Klepp K.I. Longitudinal tracking of adolescent smoking, physical activity and food choice behaviors. Am J Public Health. 1994; 84: 1121-1126 Crossref PubMed Scopus (1025) Google Scholar While primary prevention remains the ultimate goal, limitations of myocardial damage in patients with established coronary artery disease and prevention of the progression from asymptomatic left ventricular dysfunction to overt congestive heart failure may be more realistic and achievable goals. In patients with asymptomatic left ventricular dysfunction, in spite of improved medical management with ACE inhibitors and beta-blockers, clinical progression still occurs at a rate of 11%/year, 2 Colucci W.S. Packer M. Bristow M.R. et al. US Carvedilol Heart Failure Study GroupCarvedilol inhibits clinical progression in patients with mild symptoms of heart failure. Circulation. 1996; 94: 2800-2806 Crossref PubMed Scopus (588) Google Scholar suggesting that more aggressive and earlier treatment is needed and, in addition to hemodynamic and neurohormonal factors, other factors may play a role in the progression of left ventricular dysfunction." @default.
• W1915150039 created "2016-06-24" @default.
• W1915150039 creator A5062475036 @default.
• W1915150039 date "2000-08-01" @default.
• W1915150039 modified "2023-09-27" @default.
• W1915150039 title "Behavioral and environmental factors contributing to the development and progression of congestive heart failure11The author wishes to thank Tim Furlong for excellent secretarial assistance in the preparation of this manuscript." @default.
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• W1915150039 doi "https://doi.org/10.1016/s1053-2498(99)00106-0" @default.
• W1915150039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11016482" @default.
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