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- W1915907597 abstract "ABSTRACT We report the identification of a set of Legionella pneumophila genes that encode products with homology to proteins of the type II general secretion pathway of gram-negative bacteria. A strain containing a deletion-substitution mutation of two of these genes was unable to secrete the Msp protease. This strain was unable to multiply within the free-living amoeba Acanthamoeba castellanii yet was able to kill HL-60-derived macrophages. Because Msp is not required for growth in amoebae, other proteins which are important for growth in amoebae are likely secreted by this pathway." @default.
- W1915907597 created "2016-06-24" @default.
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- W1915907597 creator A5080539334 @default.
- W1915907597 date "1999-07-01" @default.
- W1915907597 modified "2023-10-10" @default.
- W1915907597 title "<i>Legionella pneumophila</i> Contains a Type II General Secretion Pathway Required for Growth in Amoebae as Well as for Secretion of the Msp Protease" @default.
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- W1915907597 doi "https://doi.org/10.1128/iai.67.7.3662-3666.1999" @default.
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