FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1916490003> ?p ?o ?g. }

• W1916490003 endingPage "8301" @default.
• W1916490003 startingPage "8295" @default.
• W1916490003 abstract "Repeated activation of neural pathways by kindling induces brief seizures, permanent increases in seizure susceptibility, neuronal loss in the hippocampus, and mossy fiber sprouting in the dentate gyrus. Because kindling induces permanent cellular alterations in hippocampal pathways that have been implicated in memory, it was of interest to determine if kindling also induces long-lasting impairments in a spatial memory task in rats. In this study, the effects of kindling on memory were investigated by assessing kindled rats in a radial arm maze behavior that is impaired by hippocampal damage. Kindled rats studied at 1 month after the last of 30–134 evoked generalized tonic-clonic seizures acquired competence in the performance of the radial arm maze task at a rate that was indistinguishable from age-matched normal controls, but demonstrated a deficit in the ability to repeat the task on consecutive days. The repetition deficit was not observed in rats that experienced three afterdischarges or three generalized tonic- clonic seizures, and the severity of the deficit varied directly with the number of evoked kindled seizures. Repeated brief seizures evoked by kindling induced a long-lasting deficit in a radial arm maze task that is a rodent model of memory. The observation of a long-lasting deficit in radial arm maze performance in kindled rats suggests that the cellular alterations induced in the hippocampus by seizures could contribute to the memory dysfunction in human epilepsy." @default.
• W1916490003 created "2016-06-24" @default.
• W1916490003 creator A5005215625 @default.
• W1916490003 creator A5034131912 @default.
• W1916490003 creator A5039402197 @default.
• W1916490003 creator A5046335402 @default.
• W1916490003 creator A5065224544 @default.
• W1916490003 date "1995-12-01" @default.
• W1916490003 modified "2023-09-27" @default.
• W1916490003 title "Deficits in radial arm maze performance in kindled rats: evidence for long-lasting memory dysfunction induced by repeated brief seizures" @default.
• W1916490003 cites W1826201647 @default.
• W1916490003 cites W1827373965 @default.
• W1916490003 cites W1875451588 @default.
• W1916490003 cites W1929312129 @default.
• W1916490003 cites W1950306692 @default.
• W1916490003 cites W1965584283 @default.
• W1916490003 cites W1984214648 @default.
• W1916490003 cites W1996457044 @default.
• W1916490003 cites W2013400604 @default.
• W1916490003 cites W2015692984 @default.
• W1916490003 cites W2017169966 @default.
• W1916490003 cites W2018061597 @default.
• W1916490003 cites W2019884656 @default.
• W1916490003 cites W2029971194 @default.
• W1916490003 cites W2031283110 @default.
• W1916490003 cites W2035562497 @default.
• W1916490003 cites W2036773579 @default.
• W1916490003 cites W2037604114 @default.
• W1916490003 cites W2042315877 @default.
• W1916490003 cites W2050490622 @default.
• W1916490003 cites W2053848346 @default.
• W1916490003 cites W2058756091 @default.
• W1916490003 cites W2059658339 @default.
• W1916490003 cites W2059815797 @default.
• W1916490003 cites W2063820576 @default.
• W1916490003 cites W2076425653 @default.
• W1916490003 cites W2077369265 @default.
• W1916490003 cites W2079882829 @default.
• W1916490003 cites W2097782952 @default.
• W1916490003 cites W2103692957 @default.
• W1916490003 cites W2106138734 @default.
• W1916490003 cites W2112549080 @default.
• W1916490003 cites W2151330572 @default.
• W1916490003 cites W2165646866 @default.
• W1916490003 cites W67219464 @default.
• W1916490003 doi "https://doi.org/10.1523/jneurosci.15-12-08295.1995" @default.
• W1916490003 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6577960" @default.
• W1916490003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8613762" @default.
• W1916490003 hasPublicationYear "1995" @default.
• W1916490003 type Work @default.
• W1916490003 sameAs 1916490003 @default.
• W1916490003 citedByCount "82" @default.
• W1916490003 countsByYear W19164900032012 @default.
• W1916490003 countsByYear W19164900032013 @default.
• W1916490003 countsByYear W19164900032014 @default.
• W1916490003 countsByYear W19164900032015 @default.
• W1916490003 countsByYear W19164900032016 @default.
• W1916490003 countsByYear W19164900032017 @default.
• W1916490003 countsByYear W19164900032019 @default.
• W1916490003 countsByYear W19164900032021 @default.
• W1916490003 crossrefType "journal-article" @default.
• W1916490003 hasAuthorship W1916490003A5005215625 @default.
• W1916490003 hasAuthorship W1916490003A5034131912 @default.
• W1916490003 hasAuthorship W1916490003A5039402197 @default.
• W1916490003 hasAuthorship W1916490003A5046335402 @default.
• W1916490003 hasAuthorship W1916490003A5065224544 @default.
• W1916490003 hasBestOaLocation W19164900031 @default.
• W1916490003 hasConcept C100691959 @default.
• W1916490003 hasConcept C13260007 @default.
• W1916490003 hasConcept C148762608 @default.
• W1916490003 hasConcept C15744967 @default.
• W1916490003 hasConcept C169760540 @default.
• W1916490003 hasConcept C169900460 @default.
• W1916490003 hasConcept C21963081 @default.
• W1916490003 hasConcept C2776464000 @default.
• W1916490003 hasConcept C2778186239 @default.
• W1916490003 hasConcept C2778302826 @default.
• W1916490003 hasConcept C2779407169 @default.
• W1916490003 hasConcept C2780566141 @default.
• W1916490003 hasConcept C2781161787 @default.
• W1916490003 hasConcept C2984915365 @default.
• W1916490003 hasConcept C3018842126 @default.
• W1916490003 hasConceptScore W1916490003C100691959 @default.
• W1916490003 hasConceptScore W1916490003C13260007 @default.
• W1916490003 hasConceptScore W1916490003C148762608 @default.
• W1916490003 hasConceptScore W1916490003C15744967 @default.
• W1916490003 hasConceptScore W1916490003C169760540 @default.
• W1916490003 hasConceptScore W1916490003C169900460 @default.
• W1916490003 hasConceptScore W1916490003C21963081 @default.
• W1916490003 hasConceptScore W1916490003C2776464000 @default.
• W1916490003 hasConceptScore W1916490003C2778186239 @default.
• W1916490003 hasConceptScore W1916490003C2778302826 @default.
• W1916490003 hasConceptScore W1916490003C2779407169 @default.
• W1916490003 hasConceptScore W1916490003C2780566141 @default.
• W1916490003 hasConceptScore W1916490003C2781161787 @default.
• W1916490003 hasConceptScore W1916490003C2984915365 @default.
• W1916490003 hasConceptScore W1916490003C3018842126 @default.
• W1916490003 hasIssue "12" @default.

• next