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• W1916949624 startingPage "61" @default.
• W1916949624 abstract "Multiciliated cells are characterized by coordinated arrays of motile cilia. In the respiratory tract, the maintenance of this array is essential to ensure proper ciliary and mucus clearance. The establishment and the maintenance of the ciliary set are mediated by the correct positioning of basal bodies at the cell cortex. While microtubule and actin cytoskeletons have been reported to regulate basal body lattices, an understanding of their detailed organization was missing until recently. Here, we describe how electron tomography can highlight the arrangement of the cytoskeletal networks and their interplay with basal bodies in ciliated cells in their tissular environment. Thanks to this approach, information in fine detail on large parts of the cell, dense in organelles, is provided. In combination with other approaches, such as transgenic animal models, electron tomography constitutes a powerful technique giving an overview of tissues and cells concomitantly with acquisition of three-dimensional detail." @default.
• W1916949624 created "2016-06-24" @default.
• W1916949624 creator A5037534881 @default.
• W1916949624 creator A5067677003 @default.
• W1916949624 creator A5073143479 @default.
• W1916949624 date "2015-01-01" @default.
• W1916949624 modified "2023-10-14" @default.
• W1916949624 title "In vivo examination of the cortical cytoskeleton in multiciliated cells using electron tomography" @default.
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• W1916949624 doi "https://doi.org/10.1016/bs.mcb.2015.03.001" @default.
• W1916949624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26175434" @default.
• W1916949624 hasPublicationYear "2015" @default.
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