FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1917097229> ?p ?o ?g. }

• W1917097229 endingPage "628" @default.
• W1917097229 startingPage "623" @default.
• W1917097229 abstract "Rhodiola rosea is a perennial plant in the Crassulaceae family, recently postulated to exert its adaptogenic functions partially by modulating the expression of molecular factors such as heat shock proteins (HSP). The aim of this study was to analyze the efficacy of a Rhodiola rosea extract (Rhodiolife) in protecting murine skeletal muscle cells (C2 C12 myotubes) from chemically induced oxidative stress and to establish whether modulation of HSP70 expression is observed. C2 C12 cells treated with Rhodiolife did not experience any loss of viability (p > 0.05) at concentrations of 1-100 µg/mL for up to 24 h. In control cultures, viability decreased 25% following exposure to 2 mM H2 O2 (1 h). However, no significant decrease in viability in cells pre-treated with extract at concentrations as low as 1 µg/mL was observed. HSP70 mRNA levels were up-regulated two-fold in cell cultures treated with Rhodiolife (10 µg/mL), and expression was further enhanced by exposure to H2 O2 (six-fold, p < 0.05). HSP70 protein levels were maintained in pre-treated cell cultures compared to controls but was significantly lower (-50%) in cells lacking treatment exposed to H2 O2 . The present results indicate that Rhodiolife protects C2 C12 myotubes against peroxide-induced oxidative stress through the modulation of the molecular chaperone HSP70." @default.
• W1917097229 created "2016-06-24" @default.
• W1917097229 creator A5060650515 @default.
• W1917097229 creator A5061443906 @default.
• W1917097229 creator A5062586227 @default.
• W1917097229 creator A5081609956 @default.
• W1917097229 date "2013-07-26" @default.
• W1917097229 modified "2023-09-26" @default.
• W1917097229 title "A Rhodiola Rosea Root Extract Protects Skeletal Muscle Cells Against Chemically Induced Oxidative Stress by Modulating Heat Shock Protein 70 (HSP70) Expression" @default.
• W1917097229 cites W1970891845 @default.
• W1917097229 cites W1972121275 @default.
• W1917097229 cites W1983671987 @default.
• W1917097229 cites W1989207373 @default.
• W1917097229 cites W1996995642 @default.
• W1917097229 cites W2000730960 @default.
• W1917097229 cites W2005317701 @default.
• W1917097229 cites W2061974364 @default.
• W1917097229 cites W2067494371 @default.
• W1917097229 cites W2067971473 @default.
• W1917097229 cites W2071960728 @default.
• W1917097229 cites W2074383932 @default.
• W1917097229 cites W2088424981 @default.
• W1917097229 cites W2094396472 @default.
• W1917097229 cites W2098553213 @default.
• W1917097229 cites W2102596758 @default.
• W1917097229 cites W2106127270 @default.
• W1917097229 cites W2109936231 @default.
• W1917097229 cites W2113448695 @default.
• W1917097229 cites W2118844654 @default.
• W1917097229 cites W2119360807 @default.
• W1917097229 cites W2125359881 @default.
• W1917097229 cites W2141410612 @default.
• W1917097229 cites W2160675155 @default.
• W1917097229 cites W2168905327 @default.
• W1917097229 cites W2175029576 @default.
• W1917097229 cites W2216471839 @default.
• W1917097229 cites W40830852 @default.
• W1917097229 doi "https://doi.org/10.1002/ptr.5046" @default.
• W1917097229 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23893458" @default.
• W1917097229 hasPublicationYear "2013" @default.
• W1917097229 type Work @default.
• W1917097229 sameAs 1917097229 @default.
• W1917097229 citedByCount "22" @default.
• W1917097229 countsByYear W19170972292015 @default.
• W1917097229 countsByYear W19170972292016 @default.
• W1917097229 countsByYear W19170972292017 @default.
• W1917097229 countsByYear W19170972292018 @default.
• W1917097229 countsByYear W19170972292019 @default.
• W1917097229 countsByYear W19170972292020 @default.
• W1917097229 countsByYear W19170972292021 @default.
• W1917097229 countsByYear W19170972292022 @default.
• W1917097229 countsByYear W19170972292023 @default.
• W1917097229 crossrefType "journal-article" @default.
• W1917097229 hasAuthorship W1917097229A5060650515 @default.
• W1917097229 hasAuthorship W1917097229A5061443906 @default.
• W1917097229 hasAuthorship W1917097229A5062586227 @default.
• W1917097229 hasAuthorship W1917097229A5081609956 @default.
• W1917097229 hasConcept C104317684 @default.
• W1917097229 hasConcept C1491633281 @default.
• W1917097229 hasConcept C153911025 @default.
• W1917097229 hasConcept C185592680 @default.
• W1917097229 hasConcept C202751555 @default.
• W1917097229 hasConcept C205260736 @default.
• W1917097229 hasConcept C2776151105 @default.
• W1917097229 hasConcept C2779526882 @default.
• W1917097229 hasConcept C2780505606 @default.
• W1917097229 hasConcept C3763915 @default.
• W1917097229 hasConcept C53227056 @default.
• W1917097229 hasConcept C55493867 @default.
• W1917097229 hasConcept C68991219 @default.
• W1917097229 hasConcept C86803240 @default.
• W1917097229 hasConcept C98274493 @default.
• W1917097229 hasConceptScore W1917097229C104317684 @default.
• W1917097229 hasConceptScore W1917097229C1491633281 @default.
• W1917097229 hasConceptScore W1917097229C153911025 @default.
• W1917097229 hasConceptScore W1917097229C185592680 @default.
• W1917097229 hasConceptScore W1917097229C202751555 @default.
• W1917097229 hasConceptScore W1917097229C205260736 @default.
• W1917097229 hasConceptScore W1917097229C2776151105 @default.
• W1917097229 hasConceptScore W1917097229C2779526882 @default.
• W1917097229 hasConceptScore W1917097229C2780505606 @default.
• W1917097229 hasConceptScore W1917097229C3763915 @default.
• W1917097229 hasConceptScore W1917097229C53227056 @default.
• W1917097229 hasConceptScore W1917097229C55493867 @default.
• W1917097229 hasConceptScore W1917097229C68991219 @default.
• W1917097229 hasConceptScore W1917097229C86803240 @default.
• W1917097229 hasConceptScore W1917097229C98274493 @default.
• W1917097229 hasIssue "4" @default.
• W1917097229 hasLocation W19170972291 @default.
• W1917097229 hasLocation W19170972292 @default.
• W1917097229 hasOpenAccess W1917097229 @default.
• W1917097229 hasPrimaryLocation W19170972291 @default.
• W1917097229 hasRelatedWork W1917097229 @default.
• W1917097229 hasRelatedWork W1932103862 @default.
• W1917097229 hasRelatedWork W2014176268 @default.
• W1917097229 hasRelatedWork W2018443879 @default.
• W1917097229 hasRelatedWork W2049680397 @default.
• W1917097229 hasRelatedWork W2171769012 @default.

• next