Matches in SemOpenAlex for { <https://semopenalex.org/work/W1917220394> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W1917220394 endingPage "232" @default.
- W1917220394 startingPage "232" @default.
- W1917220394 abstract "Background: Protocatechuic acid (PCA) is a natural phenolic acid widely distributed in plants and is considered as an active component of some traditional Chinese herbal medicines such as Cibotium barometz (L.) J.Sm, Stenoloma chusanum (L.) Ching, Ilex chinensis Sims. PCA was reported to possess various pharmacological effects which may be closely correlated with its antioxidant activities. However, the antioxidant of PCA has not been investigated systematically yet. Methods: In the study, the antioxidant activities of protocatechuic acid were measured in vitro using various antioxidant assays including 1,1-diphenyl-2-picryl-hydrazyl (DPPH•), 2,2’-azino-bis (3-ethylbenzthiazoline-6-sulfonic acid) (ABTS+•), superoxide anion radicals (•O2-) and hydroxyl radical (•OH) scavenging activity, ferric ions (Fe3+) and cupric ions (Cu2+) reducing power, ferrous ions (Fe2+) and cupric ions (Cu2+) chelating activity, compared with the positive controls Trolox or BHT.Results: In all assays, PCA along with positive controls exhibited dose-dependently antioxidant ability. Comparing to a standard antioxidant Trolox, the relative antioxidant activity of PCA (i.e. the ratio of IC50(Trolox)/IC50(PCA) ) was calculated as 2.8, 2.3, 3.7, 6.1, 4.2, 1.0, 2.7, 1.5, respectively, for DPPH, ABTS, reducing power (Fe3+), reducing power (Cu2+), superoxide anion radical-scavenging, hydroxyl radical-scavenging, chelating ability (Fe2+) and chelating ability (Cu2+). Conclusion: Comparing to Trolox, PCA shows much more effective antioxidant activity in vitro in both lipid and aqueous media. Hence, it could therefore be used in pharmacological or food industry as a natural antioxidant. It may exhibit antioxidant activity by both chelating metal transition ions as well as by scavenging free radicals via donating hydrogen atom (H•) or electron (e).Keywords: Protocatechuic acid, antioxidant, reducing power, free radical-scavenging, chelating ability." @default.
- W1917220394 created "2016-06-24" @default.
- W1917220394 creator A5014828946 @default.
- W1917220394 creator A5029711969 @default.
- W1917220394 creator A5056648062 @default.
- W1917220394 creator A5073930827 @default.
- W1917220394 date "2011-07-31" @default.
- W1917220394 modified "2023-10-02" @default.
- W1917220394 title "Antioxidant Activity and Mechanism of Protocatechuic Acid in vitro" @default.
- W1917220394 cites W1552325619 @default.
- W1917220394 cites W1977299817 @default.
- W1917220394 cites W1977740718 @default.
- W1917220394 cites W1978261908 @default.
- W1917220394 cites W1991912822 @default.
- W1917220394 cites W2000656455 @default.
- W1917220394 cites W2013014144 @default.
- W1917220394 cites W2020957717 @default.
- W1917220394 cites W2021995332 @default.
- W1917220394 cites W2026480558 @default.
- W1917220394 cites W2043520828 @default.
- W1917220394 cites W2068934649 @default.
- W1917220394 cites W2080300033 @default.
- W1917220394 cites W2088866343 @default.
- W1917220394 cites W2093086294 @default.
- W1917220394 cites W2095634841 @default.
- W1917220394 cites W2162002392 @default.
- W1917220394 cites W2165201727 @default.
- W1917220394 cites W3135624861 @default.
- W1917220394 doi "https://doi.org/10.31989/ffhd.v1i7.127" @default.
- W1917220394 hasPublicationYear "2011" @default.
- W1917220394 type Work @default.
- W1917220394 sameAs 1917220394 @default.
- W1917220394 citedByCount "177" @default.
- W1917220394 countsByYear W19172203942012 @default.
- W1917220394 countsByYear W19172203942013 @default.
- W1917220394 countsByYear W19172203942014 @default.
- W1917220394 countsByYear W19172203942015 @default.
- W1917220394 countsByYear W19172203942016 @default.
- W1917220394 countsByYear W19172203942017 @default.
- W1917220394 countsByYear W19172203942018 @default.
- W1917220394 countsByYear W19172203942019 @default.
- W1917220394 countsByYear W19172203942020 @default.
- W1917220394 countsByYear W19172203942021 @default.
- W1917220394 countsByYear W19172203942022 @default.
- W1917220394 countsByYear W19172203942023 @default.
- W1917220394 crossrefType "journal-article" @default.
- W1917220394 hasAuthorship W1917220394A5014828946 @default.
- W1917220394 hasAuthorship W1917220394A5029711969 @default.
- W1917220394 hasAuthorship W1917220394A5056648062 @default.
- W1917220394 hasAuthorship W1917220394A5073930827 @default.
- W1917220394 hasBestOaLocation W19172203941 @default.
- W1917220394 hasConcept C13965031 @default.
- W1917220394 hasConcept C178790620 @default.
- W1917220394 hasConcept C181199279 @default.
- W1917220394 hasConcept C185592680 @default.
- W1917220394 hasConcept C197404232 @default.
- W1917220394 hasConcept C2776231299 @default.
- W1917220394 hasConcept C2776778087 @default.
- W1917220394 hasConcept C2778004101 @default.
- W1917220394 hasConcept C2780795997 @default.
- W1917220394 hasConcept C2781031786 @default.
- W1917220394 hasConcept C2781203734 @default.
- W1917220394 hasConcept C2781401929 @default.
- W1917220394 hasConcept C55493867 @default.
- W1917220394 hasConceptScore W1917220394C13965031 @default.
- W1917220394 hasConceptScore W1917220394C178790620 @default.
- W1917220394 hasConceptScore W1917220394C181199279 @default.
- W1917220394 hasConceptScore W1917220394C185592680 @default.
- W1917220394 hasConceptScore W1917220394C197404232 @default.
- W1917220394 hasConceptScore W1917220394C2776231299 @default.
- W1917220394 hasConceptScore W1917220394C2776778087 @default.
- W1917220394 hasConceptScore W1917220394C2778004101 @default.
- W1917220394 hasConceptScore W1917220394C2780795997 @default.
- W1917220394 hasConceptScore W1917220394C2781031786 @default.
- W1917220394 hasConceptScore W1917220394C2781203734 @default.
- W1917220394 hasConceptScore W1917220394C2781401929 @default.
- W1917220394 hasConceptScore W1917220394C55493867 @default.
- W1917220394 hasIssue "7" @default.
- W1917220394 hasLocation W19172203941 @default.
- W1917220394 hasOpenAccess W1917220394 @default.
- W1917220394 hasPrimaryLocation W19172203941 @default.
- W1917220394 hasRelatedWork W1917220394 @default.
- W1917220394 hasRelatedWork W1991677620 @default.
- W1917220394 hasRelatedWork W2010408236 @default.
- W1917220394 hasRelatedWork W2092784860 @default.
- W1917220394 hasRelatedWork W2162213934 @default.
- W1917220394 hasRelatedWork W2261504653 @default.
- W1917220394 hasRelatedWork W2348734847 @default.
- W1917220394 hasRelatedWork W2377049663 @default.
- W1917220394 hasRelatedWork W2381986359 @default.
- W1917220394 hasRelatedWork W2385391793 @default.
- W1917220394 hasVolume "1" @default.
- W1917220394 isParatext "false" @default.
- W1917220394 isRetracted "false" @default.
- W1917220394 magId "1917220394" @default.
- W1917220394 workType "article" @default.