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- W1917223668 abstract "Current research utilizes the specific expression pattern of intermediate filaments (IF) for identifying cellular state and origin, as well as for the purpose of disease diagnosis. Nestin is commonly utilized as a specific marker and driver for CNS progenitor cell types, but in addition, nestin can be found in several mesenchymal progenitor cells, and it is constitutively expressed in a few restricted locations, such as muscle neuromuscular junctions and kidney podocytes. Alike most other members of the IF protein family, nestin filaments are dynamic, constantly being remodeled through posttranslational modifications, which alter the solubility, protein levels, and signaling capacity of the nestin filaments. Through its interactions with kinases and other signaling executors, resulting in a complex and bidirectional regulation of cell signaling events, nestin has the potential to determine whether cells divide, differentiate, migrate, or stay in place. In this review, the broad and similar roles of IFs as dynamic signaling scaffolds, is exemplified by observations of nestin functions and its interaction with the cyclin- dependent kinase 5, the atypical kinase in the family of cyclin-dependent kinases." @default.
- W1917223668 created "2016-06-24" @default.
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- W1917223668 date "2016-01-01" @default.
- W1917223668 modified "2023-10-17" @default.
- W1917223668 title "Studying Nestin and its Interrelationship with Cdk5" @default.
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- W1917223668 cites W1552651901 @default.
- W1917223668 cites W1965676841 @default.
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- W1917223668 cites W1980168406 @default.
- W1917223668 cites W1980574956 @default.
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- W1917223668 doi "https://doi.org/10.1016/bs.mie.2015.09.019" @default.
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