FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1917372938> ?p ?o ?g. }

• W1917372938 endingPage "508" @default.
• W1917372938 startingPage "499" @default.
• W1917372938 abstract "Synthesis of polyoma DNA in nuclei isolated from virus-infected 3T6 mouse fibroblasts leads to the selective labeling of replicative intermediates. Digestion of these replicative intermediates with the restriction endonuclease HpaII resulted in three highly labeled heterogeneous species in addition to the expected full-length fragments. These three species migrated more slowly in agarose than did any of the full-length restriction fragments and were shown to represent families of replication forks by criteria of sensitivity to S1 nuclease, kinetics of labeling both in vitro and in vivo, electron microscopy, and migration behavior during agarose gel electrophoresis. Subsequent digestion with other restriction enzymes showed that the two largest of the three fork bands originated from HpaII fragments 1 and 2. These fragments flank the putative terminus located 180 degrees relative to the origin. The third fork-containing band was less labeled and was derived from fragment 3, which is juxtaposed to the replication origin on the side corresponding to late transcription. A two-dimensional gel system revealed the presence of a fourth fork band, derived from fragment 4, that was obscured by full-length fragments 1 and 2 in the single-dimension electrophoresis. Resolution of the fork families revealed multiple discrete species within the major bands, implying the existence of stops or hesitations during replication of a given region of the genome. This conclusion is consistent with the presence of multiple species upon electrophoresis of the fork bands under denaturing conditions." @default.
• W1917372938 created "2016-06-24" @default.
• W1917372938 creator A5070199488 @default.
• W1917372938 creator A5089354143 @default.
• W1917372938 date "1982-11-01" @default.
• W1917372938 modified "2023-10-16" @default.
• W1917372938 title "Isolation and characterization of replication forks from discrete regions of the polyoma genome" @default.
• W1917372938 cites W1490753215 @default.
• W1917372938 cites W1497185008 @default.
• W1917372938 cites W1508253756 @default.
• W1917372938 cites W1529202463 @default.
• W1917372938 cites W1549897213 @default.
• W1917372938 cites W1594171856 @default.
• W1917372938 cites W1833418964 @default.
• W1917372938 cites W1967446284 @default.
• W1917372938 cites W1973456627 @default.
• W1917372938 cites W1980184916 @default.
• W1917372938 cites W1989283220 @default.
• W1917372938 cites W1998305786 @default.
• W1917372938 cites W2007561019 @default.
• W1917372938 cites W2014257871 @default.
• W1917372938 cites W2037957091 @default.
• W1917372938 cites W2038626846 @default.
• W1917372938 cites W2044850251 @default.
• W1917372938 cites W2051863900 @default.
• W1917372938 cites W2053497321 @default.
• W1917372938 cites W2055112313 @default.
• W1917372938 cites W2063450941 @default.
• W1917372938 cites W2065071532 @default.
• W1917372938 cites W2068024986 @default.
• W1917372938 cites W2089359857 @default.
• W1917372938 cites W2092472919 @default.
• W1917372938 cites W2316277494 @default.
• W1917372938 cites W1602992723 @default.
• W1917372938 doi "https://doi.org/10.1128/jvi.44.2.499-508.1982" @default.
• W1917372938 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/256293" @default.
• W1917372938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6183449" @default.
• W1917372938 hasPublicationYear "1982" @default.
• W1917372938 type Work @default.
• W1917372938 sameAs 1917372938 @default.
• W1917372938 citedByCount "11" @default.
• W1917372938 crossrefType "journal-article" @default.
• W1917372938 hasAuthorship W1917372938A5070199488 @default.
• W1917372938 hasAuthorship W1917372938A5089354143 @default.
• W1917372938 hasBestOaLocation W19173729381 @default.
• W1917372938 hasConcept C104317684 @default.
• W1917372938 hasConcept C116084860 @default.
• W1917372938 hasConcept C128319531 @default.
• W1917372938 hasConcept C141231307 @default.
• W1917372938 hasConcept C150194340 @default.
• W1917372938 hasConcept C153911025 @default.
• W1917372938 hasConcept C190727270 @default.
• W1917372938 hasConcept C22840021 @default.
• W1917372938 hasConcept C2777028655 @default.
• W1917372938 hasConcept C2777162945 @default.
• W1917372938 hasConcept C2777271071 @default.
• W1917372938 hasConcept C2778271344 @default.
• W1917372938 hasConcept C2778476535 @default.
• W1917372938 hasConcept C54355233 @default.
• W1917372938 hasConcept C552990157 @default.
• W1917372938 hasConcept C58337764 @default.
• W1917372938 hasConcept C73573662 @default.
• W1917372938 hasConcept C84289048 @default.
• W1917372938 hasConcept C86803240 @default.
• W1917372938 hasConceptScore W1917372938C104317684 @default.
• W1917372938 hasConceptScore W1917372938C116084860 @default.
• W1917372938 hasConceptScore W1917372938C128319531 @default.
• W1917372938 hasConceptScore W1917372938C141231307 @default.
• W1917372938 hasConceptScore W1917372938C150194340 @default.
• W1917372938 hasConceptScore W1917372938C153911025 @default.
• W1917372938 hasConceptScore W1917372938C190727270 @default.
• W1917372938 hasConceptScore W1917372938C22840021 @default.
• W1917372938 hasConceptScore W1917372938C2777028655 @default.
• W1917372938 hasConceptScore W1917372938C2777162945 @default.
• W1917372938 hasConceptScore W1917372938C2777271071 @default.
• W1917372938 hasConceptScore W1917372938C2778271344 @default.
• W1917372938 hasConceptScore W1917372938C2778476535 @default.
• W1917372938 hasConceptScore W1917372938C54355233 @default.
• W1917372938 hasConceptScore W1917372938C552990157 @default.
• W1917372938 hasConceptScore W1917372938C58337764 @default.
• W1917372938 hasConceptScore W1917372938C73573662 @default.
• W1917372938 hasConceptScore W1917372938C84289048 @default.
• W1917372938 hasConceptScore W1917372938C86803240 @default.
• W1917372938 hasIssue "2" @default.
• W1917372938 hasLocation W19173729381 @default.
• W1917372938 hasLocation W19173729382 @default.
• W1917372938 hasLocation W19173729383 @default.
• W1917372938 hasLocation W19173729384 @default.
• W1917372938 hasOpenAccess W1917372938 @default.
• W1917372938 hasPrimaryLocation W19173729381 @default.
• W1917372938 hasRelatedWork W1594611356 @default.
• W1917372938 hasRelatedWork W1917372938 @default.
• W1917372938 hasRelatedWork W1976740402 @default.
• W1917372938 hasRelatedWork W2043860143 @default.
• W1917372938 hasRelatedWork W2047817102 @default.
• W1917372938 hasRelatedWork W2059522972 @default.
• W1917372938 hasRelatedWork W2059911651 @default.
• W1917372938 hasRelatedWork W2119782974 @default.

• next