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- W1917389972 abstract "The impact of high temperatures (24 to 39°C) and low to moderately high humidities (20 to 70%) on the applicability of TLC systems for drug identification was studied during a 6 month climatologic cycle in Burkina Faso (West Africa). In general, the Rf values as observed on the plates were found to be substantially affected as compared with values obtained at temperate climates. Some TLC systems were more affected than others and the largest deviations of up to 30 Rf units were at low humidities. Tropical conditions also had a negative effect on the reproducibility of Rf values. However, when an Rf-correction procedure was applied, using reference mixtures of known drugs on each plate, accuracy as well as reproducibility of the resulting Rfc values were drastically improved and data thus corrected were found to be compatible with existing TLC data bases developed under moderate climatological conditions." @default.
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- W1917389972 date "1992-07-01" @default.
- W1917389972 modified "2023-10-02" @default.
- W1917389972 title "Impact of Tropical Conditions on Thin Layer Chromatography in Analytical Toxicology: High Temperatures and Moderate Humidities" @default.
- W1917389972 doi "https://doi.org/10.1520/jfs13283j" @default.
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