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- W1917457346 abstract "A goat given inoculations of sheep lymphocytes from cultures that produced bovine leukemia virus (BLV) died 8 years later with lymphosarcoma. The tumors were located in various lymph nodes, the mesentery, omentum, body wall, and retrobulbar tissues. The BLV had been cultured from lymphocytes during the first year after the goat's infection, and persisting BLV antibodies could be demonstrated when the animal was 7.5 years old. BLV provirus was identified by molecular hybridization in the DNA of the goat tumors at the above five locations. The tumors were similar to those found in lymphosarcoma of the adult bovine type (BLV associated). Normal goat liver, normal calf thymus, and calf-type lymphosarcoma (not BLV associated) served as negative controls. Our serologic, histologic, and molecular hybridization studies are evidence that the lymphosarcoma was induced BLV." @default.
- W1917457346 created "2016-06-24" @default.
- W1917457346 date "1981-09-01" @default.
- W1917457346 modified "2023-09-24" @default.
- W1917457346 title "Goat Lymphosarcoma From Bovine Leukemia Virus<xref ref-type=fn rid=fn2>2</xref><xref ref-type=fn rid=fn3>3</xref>" @default.
- W1917457346 doi "https://doi.org/10.1093/jnci/67.3.671" @default.
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