Matches in SemOpenAlex for { <https://semopenalex.org/work/W1917484833> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W1917484833 endingPage "9" @default.
- W1917484833 startingPage "641" @default.
- W1917484833 abstract "1. The objectives of this study were to study the flow-dependent arterial reactivity and pressure-independent arterial compliance of the calcium antagonist amlodipine in hypertensive men. 2. Twenty-one hypertensive patients were randomized to receive 2 months treatment with placebo (n = 10) or 5-10 mg amlodipine (n = 11) once a day. Non-invasive measurement of brachial artery mean blood pressure, diameter and flow (pulsed Doppler) and compliance (arterial mechanography and logarithmic elastic model) were obtained before and after drug administration. Vasoreactivity was studied by means of response of the brachial artery during exclusion of the hand and hyperaemia post-ischaemia. 3. Compared with placebo, amlodipine reduced mean blood pressure (% change +/- s.e. mean 11 +/- 1% vs 4 +/- 3%, P < 0.05), and increased arterial compliance at prevailing pressure (44 +/- 13%, vs 1 +/- 8%, P < 0.05) and at isobaric pressure (26 +/- 10% vs -3 +/- 6%, P < 0.05). A significant % change increase from baseline in brachial artery diameter between placebo and amlodipine was observed at rest (-2 +/- 3 vs 8 +/- 3%; P < 0.05), after wrist occlusion (-3 +/- 3 vs 6 +/- 2%; P < 0.05) and during reactive hyperaemia (-5 +/- 3 vs 18 +/- 5%; P < 0.05). No significant differences between amlodipine and placebo groups were observed in blood velocity after forearm manoeuvres before and after treatment. 4. No differences were observed between groups in brachial flow-dependent vasodilation.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W1917484833 created "2016-06-24" @default.
- W1917484833 creator A5068745129 @default.
- W1917484833 creator A5069376448 @default.
- W1917484833 creator A5080848758 @default.
- W1917484833 creator A5083431474 @default.
- W1917484833 date "1995-06-01" @default.
- W1917484833 modified "2023-10-03" @default.
- W1917484833 title "Amlodipine induces a flow and pressure-independent vasoactive effect on the brachial artery in hypertension." @default.
- W1917484833 cites W123332714 @default.
- W1917484833 cites W1623505186 @default.
- W1917484833 cites W1963772301 @default.
- W1917484833 cites W1968276629 @default.
- W1917484833 cites W1974600760 @default.
- W1917484833 cites W1975475560 @default.
- W1917484833 cites W1977527401 @default.
- W1917484833 cites W1978863897 @default.
- W1917484833 cites W1980551725 @default.
- W1917484833 cites W1989891515 @default.
- W1917484833 cites W1999983019 @default.
- W1917484833 cites W2002886413 @default.
- W1917484833 cites W2003468276 @default.
- W1917484833 cites W2005789713 @default.
- W1917484833 cites W2006718436 @default.
- W1917484833 cites W2011230868 @default.
- W1917484833 cites W2026031700 @default.
- W1917484833 cites W2039435453 @default.
- W1917484833 cites W2044811272 @default.
- W1917484833 cites W2051045106 @default.
- W1917484833 cites W2056986026 @default.
- W1917484833 cites W2065022712 @default.
- W1917484833 cites W2087443592 @default.
- W1917484833 cites W2088306526 @default.
- W1917484833 cites W2092808565 @default.
- W1917484833 cites W2119240627 @default.
- W1917484833 cites W2472957860 @default.
- W1917484833 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1365076" @default.
- W1917484833 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7654482" @default.
- W1917484833 hasPublicationYear "1995" @default.
- W1917484833 type Work @default.
- W1917484833 sameAs 1917484833 @default.
- W1917484833 citedByCount "5" @default.
- W1917484833 countsByYear W19174848332021 @default.
- W1917484833 crossrefType "journal-article" @default.
- W1917484833 hasAuthorship W1917484833A5068745129 @default.
- W1917484833 hasAuthorship W1917484833A5069376448 @default.
- W1917484833 hasAuthorship W1917484833A5080848758 @default.
- W1917484833 hasAuthorship W1917484833A5083431474 @default.
- W1917484833 hasConcept C120770815 @default.
- W1917484833 hasConcept C126322002 @default.
- W1917484833 hasConcept C142724271 @default.
- W1917484833 hasConcept C158846371 @default.
- W1917484833 hasConcept C164705383 @default.
- W1917484833 hasConcept C204787440 @default.
- W1917484833 hasConcept C27081682 @default.
- W1917484833 hasConcept C2777604165 @default.
- W1917484833 hasConcept C2777691872 @default.
- W1917484833 hasConcept C2779646130 @default.
- W1917484833 hasConcept C3019128504 @default.
- W1917484833 hasConcept C42219234 @default.
- W1917484833 hasConcept C71924100 @default.
- W1917484833 hasConcept C84393581 @default.
- W1917484833 hasConceptScore W1917484833C120770815 @default.
- W1917484833 hasConceptScore W1917484833C126322002 @default.
- W1917484833 hasConceptScore W1917484833C142724271 @default.
- W1917484833 hasConceptScore W1917484833C158846371 @default.
- W1917484833 hasConceptScore W1917484833C164705383 @default.
- W1917484833 hasConceptScore W1917484833C204787440 @default.
- W1917484833 hasConceptScore W1917484833C27081682 @default.
- W1917484833 hasConceptScore W1917484833C2777604165 @default.
- W1917484833 hasConceptScore W1917484833C2777691872 @default.
- W1917484833 hasConceptScore W1917484833C2779646130 @default.
- W1917484833 hasConceptScore W1917484833C3019128504 @default.
- W1917484833 hasConceptScore W1917484833C42219234 @default.
- W1917484833 hasConceptScore W1917484833C71924100 @default.
- W1917484833 hasConceptScore W1917484833C84393581 @default.
- W1917484833 hasIssue "6" @default.
- W1917484833 hasLocation W19174848331 @default.
- W1917484833 hasOpenAccess W1917484833 @default.
- W1917484833 hasPrimaryLocation W19174848331 @default.
- W1917484833 hasRelatedWork W1917484833 @default.
- W1917484833 hasRelatedWork W2008199246 @default.
- W1917484833 hasRelatedWork W2111118530 @default.
- W1917484833 hasRelatedWork W2116774812 @default.
- W1917484833 hasRelatedWork W2142037089 @default.
- W1917484833 hasRelatedWork W2149837656 @default.
- W1917484833 hasRelatedWork W2331914539 @default.
- W1917484833 hasRelatedWork W2349701033 @default.
- W1917484833 hasRelatedWork W2389694733 @default.
- W1917484833 hasRelatedWork W2391872973 @default.
- W1917484833 hasVolume "39" @default.
- W1917484833 isParatext "false" @default.
- W1917484833 isRetracted "false" @default.
- W1917484833 magId "1917484833" @default.
- W1917484833 workType "article" @default.