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- W191752697 abstract "It is essential to recognise that chloracne is always a symptom of systemic poisoning and not just a cutaneous affection. Goldmann (1973). Since most cases of mild or moderate chloracne appear fit and well such a statement may seem contradictory. May (1973). It is not. Since Chloracne appears to be the most sensitive indicator of poisoning in the human subject, Moore (1978) in most cases the systemic levels of chloracneigen are insufficient to cause target organ damage either clinically, or as assessed by laboratory investigation. There are two factors which probably make up this equation; the relationship between dose and route of absorption on the one hand, and chloracne and systemic effects on the other. Much work remains to be done in this field but one thing is certain - animal experiments demonstrate conclusively that the effects of an arbitary amount of any chloracneigenic toxin are less severe as a single dose, than if given in divided doses over a longer period." @default.
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- W191752697 date "1982-01-01" @default.
- W191752697 modified "2023-09-27" @default.
- W191752697 title "CUTANEOUS EFFECTS OF CHLORACNEIGENS" @default.
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- W191752697 doi "https://doi.org/10.1016/b978-0-08-026256-7.50051-9" @default.
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